Evaluation of the association of polymorphisms of the CYP2C8 gene with the efficacy and safety of ketorolac in patients with postoperative pain syndrome

Evaluation of the association of polymorphisms of the CYP2C8 gene with the efficacy and safety of ketorolac in patients with postoperative pain syndrome

Aim. To evaluate the possible association of CYP2C8 gene polymorphisms with the clinical efficacy and safety of ketorolac in relation to postoperative pain. Materials and methods. The study included 107 patients after video laparoscopic cholecystectomy, who received ketorolac (30 mg 2.0 w/m 3 r/d...

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Bibliographic Details
Main Authors: Andranik A. Muradian, Dmitry A. Sychev, Dmitry A. Blagovestnov, Demyan I. Petrov, Dmitry S. Skukin, Irina P. Epifanova, Zhannet A. Sozaeva, Anastasia A. Kachanova, Natalia P. Denisenko, Sherzod P. Abdullaev, Elena A. Grishina
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2022-06-01
Series:Терапевтический архив
Subjects:
cholecystitis
ketorolac
postoperative pain relief
pharmacogenetics
cyp2c8
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/108776/82887

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