Glioblastoma Stem-Like Cells: Characteristics, Microenvironment, and Therapy.

Glioblastoma Stem-Like Cells: Characteristics, Microenvironment, and Therapy.

Glioblastoma multiforme (GBM), grade IV astrocytoma, is the most fatal malignant primary brain tumor. GBM contains functional subsets of cells called glioblastoma stem-like cells (GSCs), which are radioresistant and chemoresistant and eventually lead to tumor recurrence. Recent studies showed that G...

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Bibliographic Details
Main Authors: Yang Yi, I-yun Hsieh, Xiaojia Huang, Jie Li, Wei Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Pharmacology
Subjects:
Tumor Microenvironment
nanoparticle
glioblastoma stem-like cells
Epigenetic plasticity
nanocarrier technologies
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00477/full

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