Osteoporosis and dermatoporosis: a review on the role of vitamin D
Osteoporosis (OP) and Dermatoporosis (DP) are expressions of the aging process at the skin and bone levels, respectively. Both conditions are associated with increased morbidity for elderly people, and this requires necessary interventions. They share many common risk factors; among these, vitamin D...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1231580/full |
| _version_ | 1797737415078576128 |
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| author | Fiammetta Romano Domenico Serpico Mariateresa Cantelli Antonella Di Sarno Carmine Dalia Rossana Arianna Mariarosaria Lavorgna Annamaria Colao Annamaria Colao Carolina Di Somma Carolina Di Somma |
| author_facet | Fiammetta Romano Domenico Serpico Mariateresa Cantelli Antonella Di Sarno Carmine Dalia Rossana Arianna Mariarosaria Lavorgna Annamaria Colao Annamaria Colao Carolina Di Somma Carolina Di Somma |
| author_sort | Fiammetta Romano |
| collection | DOAJ |
| description | Osteoporosis (OP) and Dermatoporosis (DP) are expressions of the aging process at the skin and bone levels, respectively. Both conditions are associated with increased morbidity for elderly people, and this requires necessary interventions. They share many common risk factors; among these, vitamin D (VD) deficiency appears to have a role. VD is involved in either disease with many mechanisms, among which immunomodulation. VD deficiency has been linked to OP because it inhibits the body’s capacity to absorb calcium and maintain optimal bone health. Available evidence suggests that proper vitaminosis D also appears to be vital in preventing skin age-related issues. DP is often seen in elderly individuals, particularly those with long-term sun exposure and a history of chronic sun damage. VD deficiency can be linked to DP, since its involvement in collagen production, epidermal barrier function, inflammation regulation, wound healing, and sun protection. Aim of this review is to summarize the most updated existing evidence on the role of VD in the development of fragility syndromes such as DP and OP and the possible benefits of VD supplementation as a simple and harmful weapon against aging. |
| first_indexed | 2024-03-12T13:28:22Z |
| format | Article |
| id | doaj.art-53f02cfc7a3049c5a3b7f9bf531d0d2c |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-03-12T13:28:22Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-53f02cfc7a3049c5a3b7f9bf531d0d2c2023-08-24T23:54:56ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922023-08-011410.3389/fendo.2023.12315801231580Osteoporosis and dermatoporosis: a review on the role of vitamin DFiammetta Romano0Domenico Serpico1Mariateresa Cantelli2Antonella Di Sarno3Carmine Dalia4Rossana Arianna5Mariarosaria Lavorgna6Annamaria Colao7Annamaria Colao8Carolina Di Somma9Carolina Di Somma10Endocrinology Diabetology and Andrology Unit, Department of Clinical Medicine and Surgery, University of Naples “Federico II”, Naples, ItalyEndocrinology Diabetology and Andrology Unit, Department of Clinical Medicine and Surgery, University of Naples “Federico II”, Naples, ItalyDermatology Unit, Department of Clinical Medicine and Surgery, University of Naples “Federico II”, Naples, ItalyEndocrinology Diabetology and Andrology Unit, Department of Clinical Medicine and Surgery, University of Naples “Federico II”, Naples, ItalyInternal Medicine S. Maria Della Pietà Hospital Nola, Nola, ItalyEndocrinology Diabetology and Andrology Unit, Department of Clinical Medicine and Surgery, University of Naples “Federico II”, Naples, ItalyEndocrinology Diabetology and Andrology Unit, Department of Clinical Medicine and Surgery, University of Naples “Federico II”, Naples, ItalyEndocrinology Diabetology and Andrology Unit, Department of Clinical Medicine and Surgery, University of Naples “Federico II”, Naples, ItalyUNESCO Chair “Education for Health and Sustainable Development”, University of Naples “Federico II”, Naples, ItalyEndocrinology Diabetology and Andrology Unit, Department of Clinical Medicine and Surgery, University of Naples “Federico II”, Naples, ItalyUNESCO Chair “Education for Health and Sustainable Development”, University of Naples “Federico II”, Naples, ItalyOsteoporosis (OP) and Dermatoporosis (DP) are expressions of the aging process at the skin and bone levels, respectively. Both conditions are associated with increased morbidity for elderly people, and this requires necessary interventions. They share many common risk factors; among these, vitamin D (VD) deficiency appears to have a role. VD is involved in either disease with many mechanisms, among which immunomodulation. VD deficiency has been linked to OP because it inhibits the body’s capacity to absorb calcium and maintain optimal bone health. Available evidence suggests that proper vitaminosis D also appears to be vital in preventing skin age-related issues. DP is often seen in elderly individuals, particularly those with long-term sun exposure and a history of chronic sun damage. VD deficiency can be linked to DP, since its involvement in collagen production, epidermal barrier function, inflammation regulation, wound healing, and sun protection. Aim of this review is to summarize the most updated existing evidence on the role of VD in the development of fragility syndromes such as DP and OP and the possible benefits of VD supplementation as a simple and harmful weapon against aging.https://www.frontiersin.org/articles/10.3389/fendo.2023.1231580/fulldermatoporosisosteoporosisskinskin agingagingglucocorticoids |
| spellingShingle | Fiammetta Romano Domenico Serpico Mariateresa Cantelli Antonella Di Sarno Carmine Dalia Rossana Arianna Mariarosaria Lavorgna Annamaria Colao Annamaria Colao Carolina Di Somma Carolina Di Somma Osteoporosis and dermatoporosis: a review on the role of vitamin D Frontiers in Endocrinology dermatoporosis osteoporosis skin skin aging aging glucocorticoids |
| title | Osteoporosis and dermatoporosis: a review on the role of vitamin D |
| title_full | Osteoporosis and dermatoporosis: a review on the role of vitamin D |
| title_fullStr | Osteoporosis and dermatoporosis: a review on the role of vitamin D |
| title_full_unstemmed | Osteoporosis and dermatoporosis: a review on the role of vitamin D |
| title_short | Osteoporosis and dermatoporosis: a review on the role of vitamin D |
| title_sort | osteoporosis and dermatoporosis a review on the role of vitamin d |
| topic | dermatoporosis osteoporosis skin skin aging aging glucocorticoids |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2023.1231580/full |
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