Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph Disease

Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph Disease

Abstract Machado-Joseph disease (MJD) or Spinocerebellar ataxia type 3 (SCA3) is the most common form of dominant SCA worldwide. Magnetic Resonance Imaging (MRI) and Proton Magnetic Resonance Spectroscopy (1H-MRS) provide promising non-invasive diagnostic and follow-up tools, also serving to evaluat...

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Bibliographic Details
Main Authors:	Catarina Oliveira Miranda, Rui Jorge Nobre, Vitor Hugo Paiva, João Valente Duarte, João Castelhano, Lorena Itatí Petrella, José Sereno, Magda Santana, Sónia Afonso, Cristina Januário, Miguel Castelo-Branco, Luís Pereira de Almeida
Format:	Article
Language:	English
Published:	BMC 2022-03-01
Series:	Acta Neuropathologica Communications
Subjects:	Machado-Joseph disease (MJD) Spinocerebellar ataxia type 3 (SCA3) Magnetic resonance imaging (MRI) Proton magnetic resonance spectroscopy (1H-MRS) biomarkers Motor performance
Online Access:	https://doi.org/10.1186/s40478-022-01329-4

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