Eccrine Porocarcinoma: Clinical and Histopathological Study of 14 Patients with Special Emphasis on Sentinel Lymph Node Biopsy
Eccrine porocarcinoma is a rare skin adnexal tumour that affects elderly people. Most eccrine porocarcinomas are stage I or II according to the American Joint Committee on Cancer. The prognosis is good in early stages, but worsens when advanced. Since information on the use of sentinel lymph node bi...
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| Format: | Article |
| Language: | English |
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Medical Journals Sweden
2023-07-01
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| Series: | Acta Dermato-Venereologica |
| Subjects: | |
| Online Access: | https://medicaljournalssweden.se/actadv/article/view/11649 |
| _version_ | 1827901451293163520 |
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| author | Anna-Stiina Meriläinen Maria von Willenbrand-Bäckmann Harri Sihto Virve Koljonen |
| author_facet | Anna-Stiina Meriläinen Maria von Willenbrand-Bäckmann Harri Sihto Virve Koljonen |
| author_sort | Anna-Stiina Meriläinen |
| collection | DOAJ |
| description | Eccrine porocarcinoma is a rare skin adnexal tumour that affects elderly people. Most eccrine porocarcinomas are stage I or II according to the American Joint Committee on Cancer. The prognosis is good in early stages, but worsens when advanced. Since information on the use of sentinel lymph node biopsy in these patients is scarce, this study examined the records of all patients with eccrine porocarcinoma treated at Helsinki University Hospital during a 17-year period and focused on sentinel lymph node biopsy patients. The study identified 14 patients (9 male, 5 female). There were 2 metastases to the lymph nodes and 2 recurrences at initial referral to our institution. All primary tumours had wide local excision and 6 patients also had sentinel lymph node biopsy, of whom none had positive lymph nodes. There were no new metastases or recurrences during follow-up. Three patients died of causes other than eccrine porocarcinoma. When comparing the wide local excision only and wide local excision with sentinel lymph node biopsy groups, no parameters reached statistical significance. The decision process of the multidisciplinary tumour board meeting on whether to perform sentinel lymph node biopsy was not clear, perhaps due to the limited knowledge of eccrine porocarcinoma. Further studies and international collaboration are warranted.
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| first_indexed | 2024-03-12T23:46:20Z |
| format | Article |
| id | doaj.art-53fae1f26787466db93edd4a75b54d0c |
| institution | Directory Open Access Journal |
| issn | 0001-5555 1651-2057 |
| language | English |
| last_indexed | 2024-03-12T23:46:20Z |
| publishDate | 2023-07-01 |
| publisher | Medical Journals Sweden |
| record_format | Article |
| series | Acta Dermato-Venereologica |
| spelling | doaj.art-53fae1f26787466db93edd4a75b54d0c2023-07-14T06:24:50ZengMedical Journals SwedenActa Dermato-Venereologica0001-55551651-20572023-07-0110310.2340/actadv.v103.11649Eccrine Porocarcinoma: Clinical and Histopathological Study of 14 Patients with Special Emphasis on Sentinel Lymph Node BiopsyAnna-Stiina Meriläinen0Maria von Willenbrand-Bäckmann1Harri Sihto2Virve Koljonen3Department of Surgery, The Central Hospital of Tavastia Proper, Hämeenlinna and University of Helsinki, FinlandDepartment of Pathology Helsinki University Hospital and University of Helsinki, FinlandDepartment of Pathology Helsinki University Hospital and University of Helsinki, FinlandDepartment of Plastic Surgery Helsinki University Hospital and University of Helsinki, FinlandEccrine porocarcinoma is a rare skin adnexal tumour that affects elderly people. Most eccrine porocarcinomas are stage I or II according to the American Joint Committee on Cancer. The prognosis is good in early stages, but worsens when advanced. Since information on the use of sentinel lymph node biopsy in these patients is scarce, this study examined the records of all patients with eccrine porocarcinoma treated at Helsinki University Hospital during a 17-year period and focused on sentinel lymph node biopsy patients. The study identified 14 patients (9 male, 5 female). There were 2 metastases to the lymph nodes and 2 recurrences at initial referral to our institution. All primary tumours had wide local excision and 6 patients also had sentinel lymph node biopsy, of whom none had positive lymph nodes. There were no new metastases or recurrences during follow-up. Three patients died of causes other than eccrine porocarcinoma. When comparing the wide local excision only and wide local excision with sentinel lymph node biopsy groups, no parameters reached statistical significance. The decision process of the multidisciplinary tumour board meeting on whether to perform sentinel lymph node biopsy was not clear, perhaps due to the limited knowledge of eccrine porocarcinoma. Further studies and international collaboration are warranted. https://medicaljournalssweden.se/actadv/article/view/11649eccrine porocarcinomasentinel lymph node biopsycase series |
| spellingShingle | Anna-Stiina Meriläinen Maria von Willenbrand-Bäckmann Harri Sihto Virve Koljonen Eccrine Porocarcinoma: Clinical and Histopathological Study of 14 Patients with Special Emphasis on Sentinel Lymph Node Biopsy Acta Dermato-Venereologica eccrine porocarcinoma sentinel lymph node biopsy case series |
| title | Eccrine Porocarcinoma: Clinical and Histopathological Study of 14 Patients with Special Emphasis on Sentinel Lymph Node Biopsy |
| title_full | Eccrine Porocarcinoma: Clinical and Histopathological Study of 14 Patients with Special Emphasis on Sentinel Lymph Node Biopsy |
| title_fullStr | Eccrine Porocarcinoma: Clinical and Histopathological Study of 14 Patients with Special Emphasis on Sentinel Lymph Node Biopsy |
| title_full_unstemmed | Eccrine Porocarcinoma: Clinical and Histopathological Study of 14 Patients with Special Emphasis on Sentinel Lymph Node Biopsy |
| title_short | Eccrine Porocarcinoma: Clinical and Histopathological Study of 14 Patients with Special Emphasis on Sentinel Lymph Node Biopsy |
| title_sort | eccrine porocarcinoma clinical and histopathological study of 14 patients with special emphasis on sentinel lymph node biopsy |
| topic | eccrine porocarcinoma sentinel lymph node biopsy case series |
| url | https://medicaljournalssweden.se/actadv/article/view/11649 |
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