The effect of delaying intrauterine insemination till 48 h after hCG injection on pregnancy rate
Objective: Intrauterine insemination (IUI) is a simple procedure which has been used to treat unexplained infertility. There is no agreement about the optimum time for IUI. An interval of only a few hours exists in which it can be performed. The aim of this study was to find out whether there is a d...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2015-12-01
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| Series: | Middle East Fertility Society Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1110569015300121 |
| _version_ | 1818953556865056768 |
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| author | Ahmed M. Kamel A.M. Hussien Emad Salah |
| author_facet | Ahmed M. Kamel A.M. Hussien Emad Salah |
| author_sort | Ahmed M. Kamel |
| collection | DOAJ |
| description | Objective: Intrauterine insemination (IUI) is a simple procedure which has been used to treat unexplained infertility. There is no agreement about the optimum time for IUI. An interval of only a few hours exists in which it can be performed. The aim of this study was to find out whether there is a difference in pregnancy rate if IUI is performed 48 h rather than later than 36 h after Human chorionic gonadotropin (hCG) Injection. Setting: infertility clinic, Kasr Alainy, Cairo University Hospital. Materials and methods: A randomized case-control prospective study in which subjects in Group A will perform IUI 48 h after hCG injection after controlled ovarian stimulation, in comparison with Group B (control) in which the IUI will be performed 36 h after hCG injection. Main outcome measures: Pregnancy rate in group A was 22.6% while group B was 10.6% (p = 0.049). The mean Number of mature follicles in group A was 2.6 ± 1 follicles, while that of group B was 2.1 ± 0.9 follicles (p = 0.002). Conclusions: A lot of controversy surrounds the correct timing of IUI. Our study showed a statistically significant increase in pregnancy rate up to 22.6% in patients performing IUI 48 h after hCG trigger, compared to the 10.6% in the patients having the procedure done 12 h earlier. |
| first_indexed | 2024-12-20T10:08:09Z |
| format | Article |
| id | doaj.art-53fdddd1900f445c86363e31c17a684e |
| institution | Directory Open Access Journal |
| issn | 1110-5690 |
| language | English |
| last_indexed | 2024-12-20T10:08:09Z |
| publishDate | 2015-12-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Middle East Fertility Society Journal |
| spelling | doaj.art-53fdddd1900f445c86363e31c17a684e2022-12-21T19:44:12ZengSpringerOpenMiddle East Fertility Society Journal1110-56902015-12-0120429029410.1016/j.mefs.2015.05.001The effect of delaying intrauterine insemination till 48 h after hCG injection on pregnancy rateAhmed M. KamelA.M. HussienEmad SalahObjective: Intrauterine insemination (IUI) is a simple procedure which has been used to treat unexplained infertility. There is no agreement about the optimum time for IUI. An interval of only a few hours exists in which it can be performed. The aim of this study was to find out whether there is a difference in pregnancy rate if IUI is performed 48 h rather than later than 36 h after Human chorionic gonadotropin (hCG) Injection. Setting: infertility clinic, Kasr Alainy, Cairo University Hospital. Materials and methods: A randomized case-control prospective study in which subjects in Group A will perform IUI 48 h after hCG injection after controlled ovarian stimulation, in comparison with Group B (control) in which the IUI will be performed 36 h after hCG injection. Main outcome measures: Pregnancy rate in group A was 22.6% while group B was 10.6% (p = 0.049). The mean Number of mature follicles in group A was 2.6 ± 1 follicles, while that of group B was 2.1 ± 0.9 follicles (p = 0.002). Conclusions: A lot of controversy surrounds the correct timing of IUI. Our study showed a statistically significant increase in pregnancy rate up to 22.6% in patients performing IUI 48 h after hCG trigger, compared to the 10.6% in the patients having the procedure done 12 h earlier.http://www.sciencedirect.com/science/article/pii/S1110569015300121Intrauterine inseminationHuman chorionic gonadotropin triggerTiming of IUI48 h after hCG injection. |
| spellingShingle | Ahmed M. Kamel A.M. Hussien Emad Salah The effect of delaying intrauterine insemination till 48 h after hCG injection on pregnancy rate Middle East Fertility Society Journal Intrauterine insemination Human chorionic gonadotropin trigger Timing of IUI 48 h after hCG injection. |
| title | The effect of delaying intrauterine insemination till 48 h after hCG injection on pregnancy rate |
| title_full | The effect of delaying intrauterine insemination till 48 h after hCG injection on pregnancy rate |
| title_fullStr | The effect of delaying intrauterine insemination till 48 h after hCG injection on pregnancy rate |
| title_full_unstemmed | The effect of delaying intrauterine insemination till 48 h after hCG injection on pregnancy rate |
| title_short | The effect of delaying intrauterine insemination till 48 h after hCG injection on pregnancy rate |
| title_sort | effect of delaying intrauterine insemination till 48 h after hcg injection on pregnancy rate |
| topic | Intrauterine insemination Human chorionic gonadotropin trigger Timing of IUI 48 h after hCG injection. |
| url | http://www.sciencedirect.com/science/article/pii/S1110569015300121 |
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