Metabolic syndrome: some results and prospects for solving the problem
Lifestyle changes associated with reduced physical activity, increased caloric content of food and a steady increase in emotional stress load cause potentiation of risk factors for cardiovascular disease. Metabolic syndrome combines hypertension, dyslipidemia, diabetes and obesity. Primary systemic...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Scientific Сentre for Family Health and Human Reproduction Problems
2016-09-01
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| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/306 |
| _version_ | 1797237403391361024 |
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| author | X. Chu O. Y. Kirgizova |
| author_facet | X. Chu O. Y. Kirgizova |
| author_sort | X. Chu |
| collection | DOAJ |
| description | Lifestyle changes associated with reduced physical activity, increased caloric content of food and a steady increase in emotional stress load cause potentiation of risk factors for cardiovascular disease. Metabolic syndrome combines hypertension, dyslipidemia, diabetes and obesity. Primary systemic insulin resistance and concomitant systemic hyperinsulinemia underlie the pathology. Insulin resistance triggers a vicious cycle of symptoms that lead to the emergence of severe cardiovascular complications. Metabolic cascade can also be initiated by obesity, which in its turn predisposes to the development of hypertension and reduction of the sensitivity of peripheral insulin receptors with subsequent accumulation of excess body weight. Treatment of metabolic syndrome should be pathogenetically substantiated and include antihypertensive, lipid-lowering, anti-thrombotic drugs on the background of a rational diet and lifestyle changes. |
| first_indexed | 2024-03-08T12:18:53Z |
| format | Article |
| id | doaj.art-5404d04ab9754631b9128d2e34a0579b |
| institution | Directory Open Access Journal |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| last_indexed | 2024-04-24T17:19:12Z |
| publishDate | 2016-09-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj.art-5404d04ab9754631b9128d2e34a0579b2024-03-28T07:49:16ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962016-09-011518719410.12737/23422306Metabolic syndrome: some results and prospects for solving the problemX. Chu0O. Y. Kirgizova1Irkutsk state Medical Academy of Continuing EducationIrkutsk state Medical Academy of Continuing EducationLifestyle changes associated with reduced physical activity, increased caloric content of food and a steady increase in emotional stress load cause potentiation of risk factors for cardiovascular disease. Metabolic syndrome combines hypertension, dyslipidemia, diabetes and obesity. Primary systemic insulin resistance and concomitant systemic hyperinsulinemia underlie the pathology. Insulin resistance triggers a vicious cycle of symptoms that lead to the emergence of severe cardiovascular complications. Metabolic cascade can also be initiated by obesity, which in its turn predisposes to the development of hypertension and reduction of the sensitivity of peripheral insulin receptors with subsequent accumulation of excess body weight. Treatment of metabolic syndrome should be pathogenetically substantiated and include antihypertensive, lipid-lowering, anti-thrombotic drugs on the background of a rational diet and lifestyle changes.https://www.actabiomedica.ru/jour/article/view/306metabolic syndromecardiovascular diseases |
| spellingShingle | X. Chu O. Y. Kirgizova Metabolic syndrome: some results and prospects for solving the problem Acta Biomedica Scientifica metabolic syndrome cardiovascular diseases |
| title | Metabolic syndrome: some results and prospects for solving the problem |
| title_full | Metabolic syndrome: some results and prospects for solving the problem |
| title_fullStr | Metabolic syndrome: some results and prospects for solving the problem |
| title_full_unstemmed | Metabolic syndrome: some results and prospects for solving the problem |
| title_short | Metabolic syndrome: some results and prospects for solving the problem |
| title_sort | metabolic syndrome some results and prospects for solving the problem |
| topic | metabolic syndrome cardiovascular diseases |
| url | https://www.actabiomedica.ru/jour/article/view/306 |
| work_keys_str_mv | AT xchu metabolicsyndromesomeresultsandprospectsforsolvingtheproblem AT oykirgizova metabolicsyndromesomeresultsandprospectsforsolvingtheproblem |