Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats
Die Dai et al. evaluate changes in the metabolomic and gut microbiome in response to experimental intestinal ischemia reperfusion (IIR) injury in rats. Their results provide further insight into how gut contents contribute to widespread injury in IIR patients.
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-09-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-022-03887-8 |
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author | Die Dai Fandie Dai Jingchao Chen Menglu Jin Mingyue Li Desheng Hu Zhi Liu Zunjian Zhang Fengguo Xu Wei-Hua Chen |
author_facet | Die Dai Fandie Dai Jingchao Chen Menglu Jin Mingyue Li Desheng Hu Zhi Liu Zunjian Zhang Fengguo Xu Wei-Hua Chen |
author_sort | Die Dai |
collection | DOAJ |
description | Die Dai et al. evaluate changes in the metabolomic and gut microbiome in response to experimental intestinal ischemia reperfusion (IIR) injury in rats. Their results provide further insight into how gut contents contribute to widespread injury in IIR patients. |
first_indexed | 2024-04-12T23:06:55Z |
format | Article |
id | doaj.art-540a3f3a361443a59a0b555331d8025a |
institution | Directory Open Access Journal |
issn | 2399-3642 |
language | English |
last_indexed | 2024-04-12T23:06:55Z |
publishDate | 2022-09-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Communications Biology |
spelling | doaj.art-540a3f3a361443a59a0b555331d8025a2022-12-22T03:12:54ZengNature PortfolioCommunications Biology2399-36422022-09-015111510.1038/s42003-022-03887-8Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in ratsDie Dai0Fandie Dai1Jingchao Chen2Menglu Jin3Mingyue Li4Desheng Hu5Zhi Liu6Zunjian Zhang7Fengguo Xu8Wei-Hua Chen9Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-Imaging, Center for Artificial Intelligence Biology, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyApplied Psychology Institution, China University of GeosciencesKey Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-Imaging, Center for Artificial Intelligence Biology, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyCollege of Life Science, Henan Normal UniversityDepartment of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Biotechnology, Huazhong University of Science and Technology, College of Life Sciences and TechnologyKey Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical UniversityKey Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical UniversityKey Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-Imaging, Center for Artificial Intelligence Biology, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyDie Dai et al. evaluate changes in the metabolomic and gut microbiome in response to experimental intestinal ischemia reperfusion (IIR) injury in rats. Their results provide further insight into how gut contents contribute to widespread injury in IIR patients.https://doi.org/10.1038/s42003-022-03887-8 |
spellingShingle | Die Dai Fandie Dai Jingchao Chen Menglu Jin Mingyue Li Desheng Hu Zhi Liu Zunjian Zhang Fengguo Xu Wei-Hua Chen Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats Communications Biology |
title | Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats |
title_full | Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats |
title_fullStr | Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats |
title_full_unstemmed | Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats |
title_short | Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats |
title_sort | integrated multi omics reveal important roles of gut contents in intestinal ischemia reperfusion induced injuries in rats |
url | https://doi.org/10.1038/s42003-022-03887-8 |
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