Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats

Die Dai et al. evaluate changes in the metabolomic and gut microbiome in response to experimental intestinal ischemia reperfusion (IIR) injury in rats. Their results provide further insight into how gut contents contribute to widespread injury in IIR patients.

Bibliographic Details
Main Authors: Die Dai, Fandie Dai, Jingchao Chen, Menglu Jin, Mingyue Li, Desheng Hu, Zhi Liu, Zunjian Zhang, Fengguo Xu, Wei-Hua Chen
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03887-8
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author Die Dai
Fandie Dai
Jingchao Chen
Menglu Jin
Mingyue Li
Desheng Hu
Zhi Liu
Zunjian Zhang
Fengguo Xu
Wei-Hua Chen
author_facet Die Dai
Fandie Dai
Jingchao Chen
Menglu Jin
Mingyue Li
Desheng Hu
Zhi Liu
Zunjian Zhang
Fengguo Xu
Wei-Hua Chen
author_sort Die Dai
collection DOAJ
description Die Dai et al. evaluate changes in the metabolomic and gut microbiome in response to experimental intestinal ischemia reperfusion (IIR) injury in rats. Their results provide further insight into how gut contents contribute to widespread injury in IIR patients.
first_indexed 2024-04-12T23:06:55Z
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issn 2399-3642
language English
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publishDate 2022-09-01
publisher Nature Portfolio
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spelling doaj.art-540a3f3a361443a59a0b555331d8025a2022-12-22T03:12:54ZengNature PortfolioCommunications Biology2399-36422022-09-015111510.1038/s42003-022-03887-8Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in ratsDie Dai0Fandie Dai1Jingchao Chen2Menglu Jin3Mingyue Li4Desheng Hu5Zhi Liu6Zunjian Zhang7Fengguo Xu8Wei-Hua Chen9Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-Imaging, Center for Artificial Intelligence Biology, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyApplied Psychology Institution, China University of GeosciencesKey Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-Imaging, Center for Artificial Intelligence Biology, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyCollege of Life Science, Henan Normal UniversityDepartment of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Biotechnology, Huazhong University of Science and Technology, College of Life Sciences and TechnologyKey Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical UniversityKey Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical UniversityKey Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-Imaging, Center for Artificial Intelligence Biology, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and TechnologyDie Dai et al. evaluate changes in the metabolomic and gut microbiome in response to experimental intestinal ischemia reperfusion (IIR) injury in rats. Their results provide further insight into how gut contents contribute to widespread injury in IIR patients.https://doi.org/10.1038/s42003-022-03887-8
spellingShingle Die Dai
Fandie Dai
Jingchao Chen
Menglu Jin
Mingyue Li
Desheng Hu
Zhi Liu
Zunjian Zhang
Fengguo Xu
Wei-Hua Chen
Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats
Communications Biology
title Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats
title_full Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats
title_fullStr Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats
title_full_unstemmed Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats
title_short Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats
title_sort integrated multi omics reveal important roles of gut contents in intestinal ischemia reperfusion induced injuries in rats
url https://doi.org/10.1038/s42003-022-03887-8
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