Low Serum Levels of Soluble Receptor Activator of Nuclear Factor κ B Ligand (sRANKL) Are Associated with Metabolic Dysregulation and Predict Long-Term Mortality in Critically Ill Patients

Low Serum Levels of Soluble Receptor Activator of Nuclear Factor κ B Ligand (sRANKL) Are Associated with Metabolic Dysregulation and Predict Long-Term Mortality in Critically Ill Patients

Soluble receptor activator of nuclear factor κ B ligand (sRANKL) is a member of the tumor necrosis factor receptor superfamily, and therefore, involved in various inflammatory processes. The role of sRANKL in the course of bone remodeling via activation of osteoclasts as well as chronic disease prog...

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Bibliographic Details
Main Authors: Tobias Puengel, Beate Weber, Theresa H. Wirtz, Lukas Buendgens, Sven H. Loosen, Lukas Geisler, Burcin Özdirik, Karim Hamesch, Samira Abu Jhaisha, Jonathan F. Brozat, Philipp Hohlstein, Albrecht Eisert, Eray Yagmur, Christian Trautwein, Frank Tacke, Alexander Koch
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Diagnostics
Subjects:
soluble receptor activator of nuclear factor κ B ligand (sRANKL)
intensive care unit (ICU)
critical illness
diabetes
glucose metabolism
adipokine
Online Access:https://www.mdpi.com/2075-4418/12/1/62

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