CTLA-4 Blockade of Natural Killer Cells Increases Cytotoxicity against Acute Lymphoid Leukaemia Cells Neda

CTLA-4 Blockade of Natural Killer Cells Increases Cytotoxicity against Acute Lymphoid Leukaemia Cells Neda

Objective: There is interest in using cytotoxic T lymphocyte antigen-4 (CTLA-4) immunotherapy to treat blood cancers.Unfortunately, patients with acute lymphoblastic leukaemia (ALL) frequently exhibit resistance to treatment and naturalkiller (NK) cell exhaustion. This study aims to increase the cyt...

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Bibliographic Details
Main Authors: Neda Parvini, Mohammad Esmaeil Akbari, Amir Ali Hamidieh, Fardin Fathi, Abbas Ali Amini, Marzieh Ebrahimi, Zakaria Vahabzadeh
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2024-02-01
Series:Cell Journal
Subjects:
ctla-4
immunotherapy
natural killer cells
nalm-6
Online Access:https://www.celljournal.org/article_710008_7d80dc9dae311eeda26d9759146ed7bc.pdf

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