“Scan-(pre)Plan-Treat” Workflow for Bone Metastases Using the Ethos Therapy System: A Single-Center, In Silico Experience

Purpose: To report on the accuracy of automated delineation, treatment plan quality, and duration of an in-silico “scan-(pre)plan-treat” (SPT) workflow for vertebral bone metastases using a 1 × 8 Gy regimen. Method and Materials: The cloud-based emulator system of the Ethos therapy system was used t...

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Main Authors: Eva Oldenburger, MD, Robin De Roover, PhD, Kenneth Poels, PhD, Tom Depuydt, PhD, Sofie Isebaert, PhD, Karin Haustermans, MD, PhD
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109423000878
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author Eva Oldenburger, MD
Robin De Roover, PhD
Kenneth Poels, PhD
Tom Depuydt, PhD
Sofie Isebaert, PhD
Karin Haustermans, MD, PhD
author_facet Eva Oldenburger, MD
Robin De Roover, PhD
Kenneth Poels, PhD
Tom Depuydt, PhD
Sofie Isebaert, PhD
Karin Haustermans, MD, PhD
author_sort Eva Oldenburger, MD
collection DOAJ
description Purpose: To report on the accuracy of automated delineation, treatment plan quality, and duration of an in-silico “scan-(pre)plan-treat” (SPT) workflow for vertebral bone metastases using a 1 × 8 Gy regimen. Method and Materials: The cloud-based emulator system of the Ethos therapy system was used to adapt an organ-at-risk-sparing preplan created on the diagnostic CT to the anatomy-of-the-day using the cone beam CT made before treatment. Results: SPT using the Ethos emulator system resulted in relatively good coverage of the PTV and acceptable dose to the OAR. Delivery time and plan homogeneity was the best for 7-field IMRT plan template. Conclusions: A SPT workflow formula results in a highly conformal treatment delivery while maintaining an acceptable timeframe for the patient on the treatment couch.
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spelling doaj.art-541090d8d7ec464d8852a33056ca55f32023-06-03T04:22:28ZengElsevierAdvances in Radiation Oncology2452-10942023-11-0186101258“Scan-(pre)Plan-Treat” Workflow for Bone Metastases Using the Ethos Therapy System: A Single-Center, In Silico ExperienceEva Oldenburger, MD0Robin De Roover, PhD1Kenneth Poels, PhD2Tom Depuydt, PhD3Sofie Isebaert, PhD4Karin Haustermans, MD, PhD5Department of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium; Department of Oncology, KU Leuven, Leuven, Belgium; Department of Palliative Care, University Hospitals Leuven, Leuven, Belgium; Corresponding author: Eva Oldenburger, MDDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium; Department of Oncology, KU Leuven, Leuven, BelgiumDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium; Department of Oncology, KU Leuven, Leuven, BelgiumDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium; Department of Oncology, KU Leuven, Leuven, BelgiumDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium; Department of Oncology, KU Leuven, Leuven, BelgiumDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium; Department of Oncology, KU Leuven, Leuven, BelgiumPurpose: To report on the accuracy of automated delineation, treatment plan quality, and duration of an in-silico “scan-(pre)plan-treat” (SPT) workflow for vertebral bone metastases using a 1 × 8 Gy regimen. Method and Materials: The cloud-based emulator system of the Ethos therapy system was used to adapt an organ-at-risk-sparing preplan created on the diagnostic CT to the anatomy-of-the-day using the cone beam CT made before treatment. Results: SPT using the Ethos emulator system resulted in relatively good coverage of the PTV and acceptable dose to the OAR. Delivery time and plan homogeneity was the best for 7-field IMRT plan template. Conclusions: A SPT workflow formula results in a highly conformal treatment delivery while maintaining an acceptable timeframe for the patient on the treatment couch.http://www.sciencedirect.com/science/article/pii/S2452109423000878
spellingShingle Eva Oldenburger, MD
Robin De Roover, PhD
Kenneth Poels, PhD
Tom Depuydt, PhD
Sofie Isebaert, PhD
Karin Haustermans, MD, PhD
“Scan-(pre)Plan-Treat” Workflow for Bone Metastases Using the Ethos Therapy System: A Single-Center, In Silico Experience
Advances in Radiation Oncology
title “Scan-(pre)Plan-Treat” Workflow for Bone Metastases Using the Ethos Therapy System: A Single-Center, In Silico Experience
title_full “Scan-(pre)Plan-Treat” Workflow for Bone Metastases Using the Ethos Therapy System: A Single-Center, In Silico Experience
title_fullStr “Scan-(pre)Plan-Treat” Workflow for Bone Metastases Using the Ethos Therapy System: A Single-Center, In Silico Experience
title_full_unstemmed “Scan-(pre)Plan-Treat” Workflow for Bone Metastases Using the Ethos Therapy System: A Single-Center, In Silico Experience
title_short “Scan-(pre)Plan-Treat” Workflow for Bone Metastases Using the Ethos Therapy System: A Single-Center, In Silico Experience
title_sort scan pre plan treat workflow for bone metastases using the ethos therapy system a single center in silico experience
url http://www.sciencedirect.com/science/article/pii/S2452109423000878
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