The primary familial brain calcification-associated protein MYORG is an α-galactosidase with restricted substrate specificity.

The primary familial brain calcification-associated protein MYORG is an α-galactosidase with restricted substrate specificity.

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Primary familial brain calcification (PFBC) is characterised by abnormal deposits of calcium phosphate within various regions of the brain that are associated with severe cognitive impairments, psychiatric conditions, and movement disorders. Recent studies in diverse populations have shown a link be...

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Bibliographic Details
Main Authors:	Richard W Meek, Jacob Brockerman, Osei B Fordwour, Wesley F Zandberg, Gideon J Davies, David J Vocadlo
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2022-09-01
Series:	PLoS Biology
Online Access:	https://doi.org/10.1371/journal.pbio.3001764

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