Mitral valve remodeling in the development of obstructive hypertrophic cardiomyopathy

Approximately 2/3 of patients with hypertrophic cardiomyopathy (HCM) have significant left ventricular outflow tract obstruction (LVOTO), which is caused by the interaction mitral valve apparatus and the hypertrophied septum. The contribution of mitral valve remodeling to the development of obstruct...

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Bibliographic Details
Main Authors: Francesco Moroni, Abhishek Chaturvedi, Ehsan Jafree, Zachary M. Gertz
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Indian Heart Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S0019483223001074
Description
Summary:Approximately 2/3 of patients with hypertrophic cardiomyopathy (HCM) have significant left ventricular outflow tract obstruction (LVOTO), which is caused by the interaction mitral valve apparatus and the hypertrophied septum. The contribution of mitral valve remodeling to the development of obstruction over time has never been described. We analyzed retrospectively 40 patients with HCM and no baseline obstruction followed up for a median of 2179 days. At follow up, 13 patients developed significant LVOTO. Patients who developed LVOTO had longer posterior leaflets and longer anterior leaflet residual length.
ISSN:0019-4832