Identification of Single Nucleotide Non-coding Driver Mutations in Cancer

Identification of Single Nucleotide Non-coding Driver Mutations in Cancer

Recent whole-genome sequencing studies have identified millions of somatic variants present in tumor samples. Most of these variants reside in non-coding regions of the genome potentially affecting transcriptional and post-transcriptional gene regulation. Although a few hallmark examples of driver m...

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Bibliographic Details
Main Authors:	Kok A. Gan, Sebastian Carrasco Pro, Jared A. Sewell, Juan I. Fuxman Bass
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-02-01
Series:	Frontiers in Genetics
Subjects:	cancer non-coding mutation driver mutation hotspot analysis motif analysis
Online Access:	https://www.frontiersin.org/article/10.3389/fgene.2018.00016/full

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