Public policy and economic dynamics of COVID-19 spread: A mathematical modeling study.

With the COVID-19 pandemic infecting millions of people, large-scale isolation policies have been enacted across the globe. To assess the impact of isolation measures on deaths, hospitalizations, and economic output, we create a mathematical model to simulate the spread of COVID-19, incorporating ef...

Full description

Bibliographic Details
Main Authors: Uri Goldsztejn, David Schwartzman, Arye Nehorai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0244174
_version_ 1819033273422053376
author Uri Goldsztejn
David Schwartzman
Arye Nehorai
author_facet Uri Goldsztejn
David Schwartzman
Arye Nehorai
author_sort Uri Goldsztejn
collection DOAJ
description With the COVID-19 pandemic infecting millions of people, large-scale isolation policies have been enacted across the globe. To assess the impact of isolation measures on deaths, hospitalizations, and economic output, we create a mathematical model to simulate the spread of COVID-19, incorporating effects of restrictive measures and segmenting the population based on health risk and economic vulnerability. Policymakers make isolation policy decisions based on current levels of disease spread and economic damage. For 76 weeks in a population of 330 million, we simulate a baseline scenario leaving strong isolation restrictions in place, rapidly reducing isolation restrictions for non-seniors shortly after outbreak containment, and gradually relaxing isolation restrictions for non-seniors. We use 76 weeks as an approximation of the time at which a vaccine will be available. In the baseline scenario, there are 235,724 deaths and the economy shrinks by 34.0%. With a rapid relaxation, a second outbreak takes place, with 525,558 deaths, and the economy shrinks by 32.3%. With a gradual relaxation, there are 262,917 deaths, and the economy shrinks by 29.8%. We also show that hospitalizations, deaths, and economic output are quite sensitive to disease spread by asymptomatic people. Strict restrictions on seniors with very gradual lifting of isolation for non-seniors results in a limited number of deaths and lesser economic damage. Therefore, we recommend this strategy and measures that reduce non-isolated disease spread to control the pandemic while making isolation economically viable.
first_indexed 2024-12-21T07:15:13Z
format Article
id doaj.art-5422aa5dd19040a2b925761ec6acfe31
institution Directory Open Access Journal
issn 1932-6203
language English
last_indexed 2024-12-21T07:15:13Z
publishDate 2020-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj.art-5422aa5dd19040a2b925761ec6acfe312022-12-21T19:11:53ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-011512e024417410.1371/journal.pone.0244174Public policy and economic dynamics of COVID-19 spread: A mathematical modeling study.Uri GoldsztejnDavid SchwartzmanArye NehoraiWith the COVID-19 pandemic infecting millions of people, large-scale isolation policies have been enacted across the globe. To assess the impact of isolation measures on deaths, hospitalizations, and economic output, we create a mathematical model to simulate the spread of COVID-19, incorporating effects of restrictive measures and segmenting the population based on health risk and economic vulnerability. Policymakers make isolation policy decisions based on current levels of disease spread and economic damage. For 76 weeks in a population of 330 million, we simulate a baseline scenario leaving strong isolation restrictions in place, rapidly reducing isolation restrictions for non-seniors shortly after outbreak containment, and gradually relaxing isolation restrictions for non-seniors. We use 76 weeks as an approximation of the time at which a vaccine will be available. In the baseline scenario, there are 235,724 deaths and the economy shrinks by 34.0%. With a rapid relaxation, a second outbreak takes place, with 525,558 deaths, and the economy shrinks by 32.3%. With a gradual relaxation, there are 262,917 deaths, and the economy shrinks by 29.8%. We also show that hospitalizations, deaths, and economic output are quite sensitive to disease spread by asymptomatic people. Strict restrictions on seniors with very gradual lifting of isolation for non-seniors results in a limited number of deaths and lesser economic damage. Therefore, we recommend this strategy and measures that reduce non-isolated disease spread to control the pandemic while making isolation economically viable.https://doi.org/10.1371/journal.pone.0244174
spellingShingle Uri Goldsztejn
David Schwartzman
Arye Nehorai
Public policy and economic dynamics of COVID-19 spread: A mathematical modeling study.
PLoS ONE
title Public policy and economic dynamics of COVID-19 spread: A mathematical modeling study.
title_full Public policy and economic dynamics of COVID-19 spread: A mathematical modeling study.
title_fullStr Public policy and economic dynamics of COVID-19 spread: A mathematical modeling study.
title_full_unstemmed Public policy and economic dynamics of COVID-19 spread: A mathematical modeling study.
title_short Public policy and economic dynamics of COVID-19 spread: A mathematical modeling study.
title_sort public policy and economic dynamics of covid 19 spread a mathematical modeling study
url https://doi.org/10.1371/journal.pone.0244174
work_keys_str_mv AT urigoldsztejn publicpolicyandeconomicdynamicsofcovid19spreadamathematicalmodelingstudy
AT davidschwartzman publicpolicyandeconomicdynamicsofcovid19spreadamathematicalmodelingstudy
AT aryenehorai publicpolicyandeconomicdynamicsofcovid19spreadamathematicalmodelingstudy