Gene Mutational Clusters in the Tumors of Colorectal Cancer Patients With a Family History of Cancer

Gene Mutational Clusters in the Tumors of Colorectal Cancer Patients With a Family History of Cancer

IntroductionFamily history is a high-risk factor for colorectal cancer (CRC). The risk comes not only from known germline mutations but also from the other family-related mechanisms. Uncovering them would be an important step to improve the diagnosis and treatment of these patients.MethodSamples fro...

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Bibliographic Details
Main Authors: He Huang, Ting Deng, Yuntong Guo, Hao Chen, Xiaolong Cui, Jingjing Duan, Yuchong Yang, Zhixin Guo, Yi Ba
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
mutation
family history
co-mutation
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.814397/full

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