The Effect of Aerobic Exercise on liver Factors in Antidote Producing Horses

Background & aim: Iran is one of the unique producers of antidote in the Middle East. The production of high-grade therapeutic serums and fewer side effects have a major impact on public health. Using sports activities as a non-pharmaceutical method can play an important role in maintaining and...

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Main Authors: F Razavi, H Zolfagharian, AA Banaeifar, R Eslami
Format: Article
Language:fas
Published: Yasuj University Of Medical Sciences 2019-12-01
Series:Armaghane Danesh Bimonthly Journal
Subjects:
Online Access:http://armaghanj.yums.ac.ir/article-1-2536-en.html
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author F Razavi
H Zolfagharian
AA Banaeifar
R Eslami
author_facet F Razavi
H Zolfagharian
AA Banaeifar
R Eslami
author_sort F Razavi
collection DOAJ
description Background & aim: Iran is one of the unique producers of antidote in the Middle East. The production of high-grade therapeutic serums and fewer side effects have a major impact on public health. Using sports activities as a non-pharmaceutical method can play an important role in maintaining and promoting animal health. The aim of the present study was to determine the effect of aerobic training on liver enzymatic factors aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) and gamma glutamyl transferase (GGT) in horse breeding horses.   Methods: In the present experimental study conducted in 2016, 16 horses in the antidote production cycle were randomly divided into two groups of venom and venom+training group for 22 weeks. The training protocol consisted of 3 sessions of aerobic exercise per week with moderate intensity. Blood samples were taken from weed vein at 3 different times: before the start of the protocol, at the end of the 11-week period, and at the end of the 22-week period. The activity of liver enzymes of AST, ALT, ALP, GGT was evaluated using Pars test kits manufactured using auto analyzer.  Data were analyzed by Repeated Measure ANOVA with LSD test and SPSS 21 for data analysis at alpha level less than 0.05.   Results: The data analysis indicated a significant decrease in the activity of ALP and GGT enzymes after 22 weeks of aerobic exercise training in the venom + training group (p=0.03). There was also a significant decrease in the activity of AST (p=0.02) and ALT (p=0.001) enzymes as a result of exercise training compared to the control group.   Conclusion: According to the results of this study, aerobic training seems to be effective in promoting horse health and reducing the effects of venom by reducing the levels of liver enzymatic activity(AST, ALT, GGT, ALP) in antidote producing horses. Further research in this area is recommended.
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spelling doaj.art-5427b4ef7acf429da1f0bdf60e941e772022-12-22T03:49:37ZfasYasuj University Of Medical SciencesArmaghane Danesh Bimonthly Journal1728-65141728-65142019-12-01245922934The Effect of Aerobic Exercise on liver Factors in Antidote Producing HorsesF Razavi0H Zolfagharian1AA Banaeifar2R Eslami3 Department of Exercise Physiology, South Tehran Branch, Islamic Azad University, Tehran ,Iran Department of Human Serum Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization(AREEO), Karaj, Iran Department of Exercise Physiology, South Tehran Branch, Islamic Azad University, Tehran ,Iran Department of Exercise Physiology, Allameh tabatabai University, Tehran, Iran. Background & aim: Iran is one of the unique producers of antidote in the Middle East. The production of high-grade therapeutic serums and fewer side effects have a major impact on public health. Using sports activities as a non-pharmaceutical method can play an important role in maintaining and promoting animal health. The aim of the present study was to determine the effect of aerobic training on liver enzymatic factors aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) and gamma glutamyl transferase (GGT) in horse breeding horses.   Methods: In the present experimental study conducted in 2016, 16 horses in the antidote production cycle were randomly divided into two groups of venom and venom+training group for 22 weeks. The training protocol consisted of 3 sessions of aerobic exercise per week with moderate intensity. Blood samples were taken from weed vein at 3 different times: before the start of the protocol, at the end of the 11-week period, and at the end of the 22-week period. The activity of liver enzymes of AST, ALT, ALP, GGT was evaluated using Pars test kits manufactured using auto analyzer.  Data were analyzed by Repeated Measure ANOVA with LSD test and SPSS 21 for data analysis at alpha level less than 0.05.   Results: The data analysis indicated a significant decrease in the activity of ALP and GGT enzymes after 22 weeks of aerobic exercise training in the venom + training group (p=0.03). There was also a significant decrease in the activity of AST (p=0.02) and ALT (p=0.001) enzymes as a result of exercise training compared to the control group.   Conclusion: According to the results of this study, aerobic training seems to be effective in promoting horse health and reducing the effects of venom by reducing the levels of liver enzymatic activity(AST, ALT, GGT, ALP) in antidote producing horses. Further research in this area is recommended.http://armaghanj.yums.ac.ir/article-1-2536-en.htmlaerobic exercisehepatic factorshorseantidote
spellingShingle F Razavi
H Zolfagharian
AA Banaeifar
R Eslami
The Effect of Aerobic Exercise on liver Factors in Antidote Producing Horses
Armaghane Danesh Bimonthly Journal
aerobic exercise
hepatic factors
horse
antidote
title The Effect of Aerobic Exercise on liver Factors in Antidote Producing Horses
title_full The Effect of Aerobic Exercise on liver Factors in Antidote Producing Horses
title_fullStr The Effect of Aerobic Exercise on liver Factors in Antidote Producing Horses
title_full_unstemmed The Effect of Aerobic Exercise on liver Factors in Antidote Producing Horses
title_short The Effect of Aerobic Exercise on liver Factors in Antidote Producing Horses
title_sort effect of aerobic exercise on liver factors in antidote producing horses
topic aerobic exercise
hepatic factors
horse
antidote
url http://armaghanj.yums.ac.ir/article-1-2536-en.html
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