The Role of Rho/Rho-Kinase Pathway in the Pathophysiology of Absence Epilepsy

The Role of Rho/Rho-Kinase Pathway in the Pathophysiology of Absence Epilepsy

Objectives:Rho/Rho-kinase (ROCK) signaling has been shown to contribute to neuroinflammation, epileptogenesis, and seizures in convulsivetype epilepsy models. However, this pathway has not been investigated in the pathophysiology of absence epilepsy. The aim of this study was to investigate ROCK act...

Full description

Bibliographic Details
Main Authors:	Nihan ÇARÇAK, Melis YAVUZ, Tuğba ERYİĞİT, Akif Hakan KURT, Meral URHAN KÜÇÜK, Filiz ONAT, Kansu BÜYÜKAFŞAR
Format:	Article
Language:	English
Published:	Galenos Yayinevi 2019-04-01
Series:	Archives of Epilepsy
Subjects:	absence epilepsy enzyme-linked immunosorbent assay rho/rho-kinase rho-kinase genetic absence epilepsy rats from strasburg y-27632
Online Access:	http://archepilepsy.org/archives/archive-detail/article-preview/the-role-of-rho-rho-kinase-pathway-in-the-pathophy/54871

Similar Items

The Functional Significance of the Rho/Rho-Kinase Pathway in Human Erythrocytes
by: R. Nalan Tiftik, et al.
Published: (2014-05-01)

ROCK (RhoA/Rho Kinase) in Cardiovascular–Renal Pathophysiology: A Review of New Advancements
by: Teresa M. Seccia, et al.
Published: (2020-05-01)

Rho-kinase inhibitors in ophthalmology
by: Megha Gopalakrishna, et al.
Published: (2021-01-01)

Effects of Short-Term Inhibition of Rho Kinase on Dromedary Camel Oocyte In Vitro Maturation
by: Hammed A. Tukur, et al.
Published: (2020-04-01)

Mechanical stress regulates gene expression via Rho/Rho-kinase signaling pathway
by: Takako Kaneko-Kawano, et al.
Published: (2015-03-01)

Extraction of active RhoGTPases by RhoGDI regulates spatiotemporal patterning of RhoGTPases
by: Adriana E Golding, et al.
Published: (2019-10-01)

Alendronate prevents angiotensin II-induced collagen I production through geranylgeranylation-dependent RhoA/Rho kinase activation in cardiac fibroblasts
by: Yang Ye, et al.
Published: (2015-12-01)

Effect of the Rho-Kinase/ROCK Signaling Pathway on Cytoskeleton Components
by: Guangzhao Guan, et al.
Published: (2023-01-01)

RhoA/Rho‐kinases in asthma: from pathogenesis to therapeutic targets
by: Yan Zhang, et al.
Published: (2020-01-01)

Effect of Anti-IL17 Antibody Treatment Alone and in Combination With Rho-Kinase Inhibitor in a Murine Model of Asthma
by: Tabata M. dos Santos, et al.
Published: (2018-09-01)

MicroRNA-141 Inhibits the Proliferation of Penile Cavernous Smooth Muscle Cells Associated with Down-Regulation of the Rhoa/Rho Kinase Signaling Pathway
by: Ying Zhang, et al.
Published: (2018-07-01)

Effect of Cigarette Smoke on Rhoa/Rho-Kinase Signalization Pathway in Lung
by: Harun Alp
Published: (2017-06-01)

RhoA/Rho kinase in spinal cord injury
by: Xiangbing Wu, et al.
Published: (2016-01-01)

Uncovering the secret life of Rho GTPases
by: Jenna A Perry, et al.
Published: (2019-12-01)

Inhibition of RhoA/Rho kinase signaling pathway by fasudil protects against kainic acid‐induced neurite injury
by: Yingchun Xiang, et al.
Published: (2021-08-01)

Inhibition of U‐II/UT signaling ameliorates cystitis‐associated bladder hyperactivity by targeting the RhoA/Rho‐kinase pathway
by: Qian Liu, et al.
Published: (2022-09-01)

Regulation of Rho GTPases by RhoGDIs in Human Cancers
by: Hee Jun Cho, et al.
Published: (2019-09-01)

Synergy by Ristocetin and CXCL12 in Human Platelet Activation: Divergent Regulation by Rho/Rho-Kinase and Rac
by: Yukiko Enomoto, et al.
Published: (2023-06-01)

Investigation of Rho-Kinase Expressions and Polymorphisms in Mantle Cell Lymphoma Patients
by: Didar Yanardağ Açık, et al.
Published: (2016-05-01)

Rho/ROCK Pathway and Noncoding RNAs: Implications in Ischemic Stroke and Spinal Cord Injury
by: Tetsu Kimura, et al.
Published: (2021-10-01)

MicroRNA Regulation of the Small Rho GTPase Regulators—Complexities and Opportunities in Targeting Cancer Metastasis
by: Brock A. Humphries, et al.
Published: (2020-04-01)

The RhoGAP activity of CYK-4/MgcRacGAP functions non-canonically by promoting RhoA activation during cytokinesis
by: Donglei Zhang, et al.
Published: (2015-08-01)

Comparative investigation of antitumoral effectiveness of Rho-kinase inhibitor Y-27632, pravastatin and atorvastatin in anaplastic thyroid cancer cell culture
by: Erdinc Nayir, et al.
Published: (2017-07-01)

Simvastatin and ROCK Inhibitor Y-27632 Inhibit Myofibroblast Differentiation of Graves’ Ophthalmopathy-Derived Orbital Fibroblasts via RhoA-Mediated ERK and p38 Signaling Pathways
by: Yi-Hsuan Wei, et al.
Published: (2021-02-01)

Rho Family GTPases in Fission Yeast Cytokinesis
by: Brian Hercyk, et al.
Published: (2019-01-01)

Inhibition of Rho-Associated Kinase Suppresses Medulloblastoma Growth
by: Cecilia Dyberg, et al.
Published: (2019-12-01)

Multifaceted Rho GTPase Signaling at the Endomembranes
by: Santosh Phuyal, et al.
Published: (2019-07-01)

Influence of Rho/ROCK inhibitor Y-27632 on proliferation of equine mesenchymal stromal cells
by: Michaela Melzer, et al.
Published: (2023-06-01)

New Angle of View on the Role of Rho/Rho Kinase Pathway in Human Diseases
by: Wei Luo, et al.
Published: (2014-12-01)

Rho-Kinase Inhibitors as Emerging Targets for Glaucoma Therapy
by: Jun Wang, et al.
Published: (2023-10-01)

Expression and clinical significance of RhoC and RhoGDIa in non-small cell lung cancer
by: Yuchen HAN, et al.
Published: (2008-06-01)

Angiotensin II Silencing Alleviates Erectile Dysfunction Through Down-Regulating the Rhoa/Rho Kinase Signaling Pathway in Rats with Diabetes Mellitus
by: Ying Zhang, et al.
Published: (2018-01-01)

Rho Family of Ras-Like GTPases in Early-Branching Animals
by: Silvestar Beljan, et al.
Published: (2020-10-01)

Skin Cancers and the Contribution of Rho GTPase Signaling Networks to Their Progression
by: Alessandra Pecora, et al.
Published: (2021-08-01)

Dysregulation of Rac or Rho elicits death of motor neurons and activation of these GTPases is altered in the G93A mutant hSOD1 mouse model of amyotrophic lateral sclerosis
by: Trisha R. Stankiewicz, et al.
Published: (2020-03-01)

Role of RhoA/Rho kinase signaling pathway in microgroove induced stem cell myogenic differentiation
by: Li, Huaqiong, et al.
Published: (2018)

Astrocytes as a target for therapeutic strategies in epilepsy: current insights
by: Nihan Çarçak, et al.
Published: (2023-07-01)

The Role of RhoA, RhoB and RhoC GTPases in Cell Morphology, Proliferation and Migration in Human Cytomegalovirus (HCMV) Infected Glioblastoma Cells
by: Melpomeni Tseliou, et al.
Published: (2016-01-01)

RNA Interference Screening Identifies Novel Roles for RhoBTB1 and RhoBTB3 in Membrane Trafficking Events in Mammalian Cells
by: Maeve Long, et al.
Published: (2020-04-01)

Rho GTPases in ameloblast differentiation
by: Keishi Otsu, et al.
Published: (2016-05-01)