The Study of Exposure to Isophorone and the Risk of Getting Cancer: A Systematic Review and Meta-analysis Protocol

Background: This protocol recommends ways to conduct a systematic review and meta-analysis on the association between isophorone exposure and cancer risk. Methods: This study will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Eligible studies wil...

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Main Authors: Tina Khavari, Fatemeh Azizi, Fatameh Asadipour, Mojtaba Azari, Mohammad Reza Taherian, Mobina Karimiyan, Yaser Soleimani, Aram Halimi, Alireza Mosavi Jarrahi
Format: Article
Language:English
Published: West Asia Organization for Cancer Prevention 2023-11-01
Series:Asian Pacific Journal of Environment and Cancer
Subjects:
Online Access:http://www.waocp.com/journal/index.php/apjec/article/view/1234
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author Tina Khavari
Fatemeh Azizi
Fatameh Asadipour
Mojtaba Azari
Mohammad Reza Taherian
Mobina Karimiyan
Yaser Soleimani
Aram Halimi
Alireza Mosavi Jarrahi
author_facet Tina Khavari
Fatemeh Azizi
Fatameh Asadipour
Mojtaba Azari
Mohammad Reza Taherian
Mobina Karimiyan
Yaser Soleimani
Aram Halimi
Alireza Mosavi Jarrahi
author_sort Tina Khavari
collection DOAJ
description Background: This protocol recommends ways to conduct a systematic review and meta-analysis on the association between isophorone exposure and cancer risk. Methods: This study will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Eligible studies will include observational research examining the association between isophorone exposure and cancer outcomes. General search terms will be used to search databases such as PubMed, Web of Science, and Scopus. Two independent reviewers will screen articles, extract data, and assess study quality and risk of bias. Data synthesis and analysis will include meta-analysis, subgroup analyses, sensitivity analyses, and assessment of publication bias. Results: The systematic review and meta-analysis will provide a comprehensive assessment of the association between isophorone exposure and cancer risk. Data from multiple studies will be pooled to achieve an overall estimate of the association, considering sources of heterogeneity and evaluating the quality of included studies. Publication bias will also be assessed. The findings will contribute to our understanding of the potential health effects of isophorone exposure and inform future research and decision-making. Conclusion: This protocol outlines a systematic and transparent approach to assessing the association between isophorone exposure and the risk of cancer. This study will provide insights into the potential health implications of isophorone exposure, preventive measures, and regulatory decisions. By following established guidelines and employing methodology, this study will provide an evidence-based assessment of the available literature, advancing our understanding of the association between isophorone exposure and cancer risk.
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spelling doaj.art-54304e6289ca4c4dbfd3376b1027e79a2024-02-03T07:34:26ZengWest Asia Organization for Cancer PreventionAsian Pacific Journal of Environment and Cancer2645-54042023-11-016116116510.31557/apjec.2023.6.1.161-1651234The Study of Exposure to Isophorone and the Risk of Getting Cancer: A Systematic Review and Meta-analysis ProtocolTina Khavari0Fatemeh Azizi1Fatameh Asadipour2Mojtaba Azari3Mohammad Reza Taherian4Mobina Karimiyan5Yaser Soleimani6Aram Halimi7Alireza Mosavi Jarrahi8Department of Occupational Health and Safety, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Occupational Health and Safety, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Occupational Health and Safety, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Occupational Health Engineering, Student Research Committee, Sabzevar University of Medical Sciences, Sabzevar, Iran.Medical School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Medical School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Cancer Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Background: This protocol recommends ways to conduct a systematic review and meta-analysis on the association between isophorone exposure and cancer risk. Methods: This study will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Eligible studies will include observational research examining the association between isophorone exposure and cancer outcomes. General search terms will be used to search databases such as PubMed, Web of Science, and Scopus. Two independent reviewers will screen articles, extract data, and assess study quality and risk of bias. Data synthesis and analysis will include meta-analysis, subgroup analyses, sensitivity analyses, and assessment of publication bias. Results: The systematic review and meta-analysis will provide a comprehensive assessment of the association between isophorone exposure and cancer risk. Data from multiple studies will be pooled to achieve an overall estimate of the association, considering sources of heterogeneity and evaluating the quality of included studies. Publication bias will also be assessed. The findings will contribute to our understanding of the potential health effects of isophorone exposure and inform future research and decision-making. Conclusion: This protocol outlines a systematic and transparent approach to assessing the association between isophorone exposure and the risk of cancer. This study will provide insights into the potential health implications of isophorone exposure, preventive measures, and regulatory decisions. By following established guidelines and employing methodology, this study will provide an evidence-based assessment of the available literature, advancing our understanding of the association between isophorone exposure and cancer risk.http://www.waocp.com/journal/index.php/apjec/article/view/1234isophorone, industrial solvent, cancer risk
spellingShingle Tina Khavari
Fatemeh Azizi
Fatameh Asadipour
Mojtaba Azari
Mohammad Reza Taherian
Mobina Karimiyan
Yaser Soleimani
Aram Halimi
Alireza Mosavi Jarrahi
The Study of Exposure to Isophorone and the Risk of Getting Cancer: A Systematic Review and Meta-analysis Protocol
Asian Pacific Journal of Environment and Cancer
isophorone, industrial solvent, cancer risk
title The Study of Exposure to Isophorone and the Risk of Getting Cancer: A Systematic Review and Meta-analysis Protocol
title_full The Study of Exposure to Isophorone and the Risk of Getting Cancer: A Systematic Review and Meta-analysis Protocol
title_fullStr The Study of Exposure to Isophorone and the Risk of Getting Cancer: A Systematic Review and Meta-analysis Protocol
title_full_unstemmed The Study of Exposure to Isophorone and the Risk of Getting Cancer: A Systematic Review and Meta-analysis Protocol
title_short The Study of Exposure to Isophorone and the Risk of Getting Cancer: A Systematic Review and Meta-analysis Protocol
title_sort study of exposure to isophorone and the risk of getting cancer a systematic review and meta analysis protocol
topic isophorone, industrial solvent, cancer risk
url http://www.waocp.com/journal/index.php/apjec/article/view/1234
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