GL-II-73, a Positive Allosteric Modulator of α5GABA<sub>A</sub> Receptors, Reverses Dopamine System Dysfunction Associated with Pilocarpine-Induced Temporal Lobe Epilepsy

Although seizures are a hallmark feature of temporal lobe epilepsy (TLE), psychiatric comorbidities, including psychosis, are frequently associated with TLE and contribute to decreased quality of life. Currently, there are no defined therapeutic protocols to manage psychosis in TLE patients, as anti...

Full description

Bibliographic Details
Main Authors: Alexandra M. McCoy, Thomas D. Prevot, Dishary Sharmin, James M. Cook, Etienne L. Sibille, Daniel J. Lodge
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/14/11588