Trivalent mRNA vaccine-candidate against seasonal flu with cross-specific humoral immune response

Trivalent mRNA vaccine-candidate against seasonal flu with cross-specific humoral immune response

Seasonal influenza remains a serious global health problem, leading to high mortality rates among the elderly and individuals with comorbidities. Vaccination is generally accepted as the most effective strategy for influenza prevention. While current influenza vaccines are effective, they still have...

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Bibliographic Details
Main Authors: Elena P. Mazunina, Vladimir A. Gushchin, Denis A. Kleymenov, Andrei E. Siniavin, Elena I. Burtseva, Maksim M. Shmarov, Evgenya A. Mukasheva, Evgeniia N. Bykonia, Sofia R. Kozlova, Elina A. Evgrafova, Anastasia N. Zolotar, Elena V. Shidlovskaya, Elena S. Kirillova, Anastasiya S. Krepkaia, Evgeny V. Usachev, Nadezhda A. Kuznetsova, Igor A. Ivanov, Sergey E. Dmitriev, Roman A. Ivanov, Denis Y. Logunov, Alexander L. Gintsburg
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
seasonal influenza
vaccine
mRNA
immunogenicity
efficacy
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1381508/full

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