Anti-Fouling Strategies of Electrochemical Sensors for Tumor Markers

The early detection and prognosis of cancers require sensitive and accurate detection methods; with developments in medicine, electrochemical biosensors have been developed that can meet these clinical needs. However, the composition of biological samples represented by serum is complex; when substa...

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Main Authors: Ge Song, Hongliang Han, Zhanfang Ma
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/23/11/5202
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author Ge Song
Hongliang Han
Zhanfang Ma
author_facet Ge Song
Hongliang Han
Zhanfang Ma
author_sort Ge Song
collection DOAJ
description The early detection and prognosis of cancers require sensitive and accurate detection methods; with developments in medicine, electrochemical biosensors have been developed that can meet these clinical needs. However, the composition of biological samples represented by serum is complex; when substances undergo non-specific adsorption to an electrode and cause fouling, the sensitivity and accuracy of the electrochemical sensor are affected. In order to reduce the effects of fouling on electrochemical sensors, a variety of anti-fouling materials and methods have been developed, and enormous progress has been made over the past few decades. Herein, the recent advances in anti-fouling materials and strategies for using electrochemical sensors for tumor markers are reviewed; we focus on new anti-fouling methods that separate the immunorecognition and signal readout platforms.
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spelling doaj.art-54386cb59a414ea3b6f90a224950f4ef2023-11-18T08:33:56ZengMDPI AGSensors1424-82202023-05-012311520210.3390/s23115202Anti-Fouling Strategies of Electrochemical Sensors for Tumor MarkersGe Song0Hongliang Han1Zhanfang Ma2Department of Chemistry, Capital Normal University, Beijing 100048, ChinaDepartment of Chemistry, Capital Normal University, Beijing 100048, ChinaDepartment of Chemistry, Capital Normal University, Beijing 100048, ChinaThe early detection and prognosis of cancers require sensitive and accurate detection methods; with developments in medicine, electrochemical biosensors have been developed that can meet these clinical needs. However, the composition of biological samples represented by serum is complex; when substances undergo non-specific adsorption to an electrode and cause fouling, the sensitivity and accuracy of the electrochemical sensor are affected. In order to reduce the effects of fouling on electrochemical sensors, a variety of anti-fouling materials and methods have been developed, and enormous progress has been made over the past few decades. Herein, the recent advances in anti-fouling materials and strategies for using electrochemical sensors for tumor markers are reviewed; we focus on new anti-fouling methods that separate the immunorecognition and signal readout platforms.https://www.mdpi.com/1424-8220/23/11/5202anti-foulingelectrochemical sensortumor markers
spellingShingle Ge Song
Hongliang Han
Zhanfang Ma
Anti-Fouling Strategies of Electrochemical Sensors for Tumor Markers
Sensors
anti-fouling
electrochemical sensor
tumor markers
title Anti-Fouling Strategies of Electrochemical Sensors for Tumor Markers
title_full Anti-Fouling Strategies of Electrochemical Sensors for Tumor Markers
title_fullStr Anti-Fouling Strategies of Electrochemical Sensors for Tumor Markers
title_full_unstemmed Anti-Fouling Strategies of Electrochemical Sensors for Tumor Markers
title_short Anti-Fouling Strategies of Electrochemical Sensors for Tumor Markers
title_sort anti fouling strategies of electrochemical sensors for tumor markers
topic anti-fouling
electrochemical sensor
tumor markers
url https://www.mdpi.com/1424-8220/23/11/5202
work_keys_str_mv AT gesong antifoulingstrategiesofelectrochemicalsensorsfortumormarkers
AT honglianghan antifoulingstrategiesofelectrochemicalsensorsfortumormarkers
AT zhanfangma antifoulingstrategiesofelectrochemicalsensorsfortumormarkers