Clostridioides difficile bile salt hydrolase activity has substrate specificity and affects biofilm formation

Clostridioides difficile bile salt hydrolase activity has substrate specificity and affects biofilm formation

Abstract The Clostridioides difficile pathogen is responsible for nosocomial infections. Germination is an essential step for the establishment of C. difficile infection (CDI) because toxins that are secreted by vegetative cells are responsible for the symptoms of CDI. Germination can be stimulated...

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Bibliographic Details
Main Authors: Andrea Martinez Aguirre, Adegoke Oyeleye Adegbite, Joseph A. Sorg
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-022-00358-0

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