Off-Label Use of Bedaquiline in Children and Adolescents with Multidrug-Resistant Tuberculosis
We describe 27 children and adolescents <18 years of age who received bedaquiline during treatment for multidrug-resistant tuberculosis. We report good treatment responses and no cessation attributable to adverse effects. Bedaquiline could be considered for use with this age group for multidrug-r...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
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Centers for Disease Control and Prevention
2017-10-01
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Series: | Emerging Infectious Diseases |
Subjects: | |
Online Access: | https://wwwnc.cdc.gov/eid/article/23/10/17-0303_article |
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author | Jay Achar Cathy Hewison Ana P. Cavalheiro Alena Skrahina Junia Cajazeiro Parpieva Nargiza Krzysztof Herboczek Assliddin S. Rajabov Jennifer Hughes Gabriella Ferlazzo James A. Seddon Philipp du Cros |
author_facet | Jay Achar Cathy Hewison Ana P. Cavalheiro Alena Skrahina Junia Cajazeiro Parpieva Nargiza Krzysztof Herboczek Assliddin S. Rajabov Jennifer Hughes Gabriella Ferlazzo James A. Seddon Philipp du Cros |
author_sort | Jay Achar |
collection | DOAJ |
description | We describe 27 children and adolescents <18 years of age who received bedaquiline during treatment for multidrug-resistant tuberculosis. We report good treatment responses and no cessation attributable to adverse effects. Bedaquiline could be considered for use with this age group for multidrug-resistant tuberculosis when treatment options are limited. |
first_indexed | 2024-12-13T12:28:52Z |
format | Article |
id | doaj.art-544059b4ad5c40e8a553eb2fbb726833 |
institution | Directory Open Access Journal |
issn | 1080-6040 1080-6059 |
language | English |
last_indexed | 2024-12-13T12:28:52Z |
publishDate | 2017-10-01 |
publisher | Centers for Disease Control and Prevention |
record_format | Article |
series | Emerging Infectious Diseases |
spelling | doaj.art-544059b4ad5c40e8a553eb2fbb7268332022-12-21T23:46:08ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592017-10-0123101711171310.3201/eid2310.170303Off-Label Use of Bedaquiline in Children and Adolescents with Multidrug-Resistant TuberculosisJay AcharCathy HewisonAna P. CavalheiroAlena SkrahinaJunia CajazeiroParpieva NargizaKrzysztof HerboczekAssliddin S. RajabovJennifer HughesGabriella FerlazzoJames A. SeddonPhilipp du CrosWe describe 27 children and adolescents <18 years of age who received bedaquiline during treatment for multidrug-resistant tuberculosis. We report good treatment responses and no cessation attributable to adverse effects. Bedaquiline could be considered for use with this age group for multidrug-resistant tuberculosis when treatment options are limited.https://wwwnc.cdc.gov/eid/article/23/10/17-0303_articleMDR TBXDR TBpediatrictreatmentbedaquilinetuberculosis |
spellingShingle | Jay Achar Cathy Hewison Ana P. Cavalheiro Alena Skrahina Junia Cajazeiro Parpieva Nargiza Krzysztof Herboczek Assliddin S. Rajabov Jennifer Hughes Gabriella Ferlazzo James A. Seddon Philipp du Cros Off-Label Use of Bedaquiline in Children and Adolescents with Multidrug-Resistant Tuberculosis Emerging Infectious Diseases MDR TB XDR TB pediatric treatment bedaquiline tuberculosis |
title | Off-Label Use of Bedaquiline in Children and Adolescents with Multidrug-Resistant Tuberculosis |
title_full | Off-Label Use of Bedaquiline in Children and Adolescents with Multidrug-Resistant Tuberculosis |
title_fullStr | Off-Label Use of Bedaquiline in Children and Adolescents with Multidrug-Resistant Tuberculosis |
title_full_unstemmed | Off-Label Use of Bedaquiline in Children and Adolescents with Multidrug-Resistant Tuberculosis |
title_short | Off-Label Use of Bedaquiline in Children and Adolescents with Multidrug-Resistant Tuberculosis |
title_sort | off label use of bedaquiline in children and adolescents with multidrug resistant tuberculosis |
topic | MDR TB XDR TB pediatric treatment bedaquiline tuberculosis |
url | https://wwwnc.cdc.gov/eid/article/23/10/17-0303_article |
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