A Simplified Herbal Formula Improves Cardiac Function and Reduces Inflammation in Mice Through the TLR-Mediated NF-κB Signaling Pathway

A Simplified Herbal Formula Improves Cardiac Function and Reduces Inflammation in Mice Through the TLR-Mediated NF-κB Signaling Pathway

Nuanxinkang tablet (NXK), a Chinese herbal formula, can improve heart function and quality of life in patients with chronic heart failure (CHF). However, the mechanisms of action of NXK are not fully understood. In this study, we investigated the effects of NXK on inflammation in the CHF mouse model...

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Bibliographic Details
Main Authors: Xiaoming Dong, Xiaowei Han, Xiaojiao Zhang, Sijing Li, Ziru Li, Jinhua Kang, Jialin Jiang, Shihao Ni, Lu Lu, Zhiling He, Haoming Huang, Shaoxiang Xian, Tianhui Yuan, Zhongqi Yang, Wenjie Long, Zemin Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
chronic heart failure
inflammation
Chinese medicine
Nuanxinkang tablet
TLR-mediated NF-κB signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.865614/full

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