Pemphigus herpetiformis with atypical features
Pemphigus herpetiformis (PH) is considered as an uncommon and mild variant of pemphigus. Here, we report the case of a 34-year-old woman who presented with intensely pruritic, annular crusted lesions with vesicles arranged in the periphery over the abdomen, back, and scalp. Cutaneous features were c...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2022-01-01
|
Series: | Clinical Dermatology Review |
Subjects: | |
Online Access: | http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2022;volume=6;issue=2;spage=154;epage=154;aulast=Arora |
_version_ | 1797998922922196992 |
---|---|
author | Sukriti Arora Raghavendra Rao |
author_facet | Sukriti Arora Raghavendra Rao |
author_sort | Sukriti Arora |
collection | DOAJ |
description | Pemphigus herpetiformis (PH) is considered as an uncommon and mild variant of pemphigus. Here, we report the case of a 34-year-old woman who presented with intensely pruritic, annular crusted lesions with vesicles arranged in the periphery over the abdomen, back, and scalp. Cutaneous features were consistent with the clinical diagnosis of PH. However, she had certain unusual clinicoimmunopathological features. She also had oral erosions, which is a rare finding in this variant of pemphigus. The results of histopathological examination and enzyme-linked immunosorbent assay were also in line with the diagnosis of pemphigus vulgaris. She responded well to dapsone with significant objective and subjective improvement in 1-week follow-up. |
first_indexed | 2024-04-11T10:55:17Z |
format | Article |
id | doaj.art-5442d927be5742f39b189e5c106410d0 |
institution | Directory Open Access Journal |
issn | 2542-551X 2542-5528 |
language | English |
last_indexed | 2024-04-11T10:55:17Z |
publishDate | 2022-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Clinical Dermatology Review |
spelling | doaj.art-5442d927be5742f39b189e5c106410d02022-12-22T04:28:46ZengWolters Kluwer Medknow PublicationsClinical Dermatology Review2542-551X2542-55282022-01-016215415410.4103/cdr.cdr_14_21Pemphigus herpetiformis with atypical featuresSukriti AroraRaghavendra RaoPemphigus herpetiformis (PH) is considered as an uncommon and mild variant of pemphigus. Here, we report the case of a 34-year-old woman who presented with intensely pruritic, annular crusted lesions with vesicles arranged in the periphery over the abdomen, back, and scalp. Cutaneous features were consistent with the clinical diagnosis of PH. However, she had certain unusual clinicoimmunopathological features. She also had oral erosions, which is a rare finding in this variant of pemphigus. The results of histopathological examination and enzyme-linked immunosorbent assay were also in line with the diagnosis of pemphigus vulgaris. She responded well to dapsone with significant objective and subjective improvement in 1-week follow-up.http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2022;volume=6;issue=2;spage=154;epage=154;aulast=Aroradesmoglein 1 and 3 enzyme-linked immunosorbent assaypemphigus herpetiformissuprabasal cleft |
spellingShingle | Sukriti Arora Raghavendra Rao Pemphigus herpetiformis with atypical features Clinical Dermatology Review desmoglein 1 and 3 enzyme-linked immunosorbent assay pemphigus herpetiformis suprabasal cleft |
title | Pemphigus herpetiformis with atypical features |
title_full | Pemphigus herpetiformis with atypical features |
title_fullStr | Pemphigus herpetiformis with atypical features |
title_full_unstemmed | Pemphigus herpetiformis with atypical features |
title_short | Pemphigus herpetiformis with atypical features |
title_sort | pemphigus herpetiformis with atypical features |
topic | desmoglein 1 and 3 enzyme-linked immunosorbent assay pemphigus herpetiformis suprabasal cleft |
url | http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2022;volume=6;issue=2;spage=154;epage=154;aulast=Arora |
work_keys_str_mv | AT sukritiarora pemphigusherpetiformiswithatypicalfeatures AT raghavendrarao pemphigusherpetiformiswithatypicalfeatures |