Pemphigus herpetiformis with atypical features

Pemphigus herpetiformis (PH) is considered as an uncommon and mild variant of pemphigus. Here, we report the case of a 34-year-old woman who presented with intensely pruritic, annular crusted lesions with vesicles arranged in the periphery over the abdomen, back, and scalp. Cutaneous features were c...

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Main Authors: Sukriti Arora, Raghavendra Rao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Clinical Dermatology Review
Subjects:
Online Access:http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2022;volume=6;issue=2;spage=154;epage=154;aulast=Arora
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author Sukriti Arora
Raghavendra Rao
author_facet Sukriti Arora
Raghavendra Rao
author_sort Sukriti Arora
collection DOAJ
description Pemphigus herpetiformis (PH) is considered as an uncommon and mild variant of pemphigus. Here, we report the case of a 34-year-old woman who presented with intensely pruritic, annular crusted lesions with vesicles arranged in the periphery over the abdomen, back, and scalp. Cutaneous features were consistent with the clinical diagnosis of PH. However, she had certain unusual clinicoimmunopathological features. She also had oral erosions, which is a rare finding in this variant of pemphigus. The results of histopathological examination and enzyme-linked immunosorbent assay were also in line with the diagnosis of pemphigus vulgaris. She responded well to dapsone with significant objective and subjective improvement in 1-week follow-up.
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spelling doaj.art-5442d927be5742f39b189e5c106410d02022-12-22T04:28:46ZengWolters Kluwer Medknow PublicationsClinical Dermatology Review2542-551X2542-55282022-01-016215415410.4103/cdr.cdr_14_21Pemphigus herpetiformis with atypical featuresSukriti AroraRaghavendra RaoPemphigus herpetiformis (PH) is considered as an uncommon and mild variant of pemphigus. Here, we report the case of a 34-year-old woman who presented with intensely pruritic, annular crusted lesions with vesicles arranged in the periphery over the abdomen, back, and scalp. Cutaneous features were consistent with the clinical diagnosis of PH. However, she had certain unusual clinicoimmunopathological features. She also had oral erosions, which is a rare finding in this variant of pemphigus. The results of histopathological examination and enzyme-linked immunosorbent assay were also in line with the diagnosis of pemphigus vulgaris. She responded well to dapsone with significant objective and subjective improvement in 1-week follow-up.http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2022;volume=6;issue=2;spage=154;epage=154;aulast=Aroradesmoglein 1 and 3 enzyme-linked immunosorbent assaypemphigus herpetiformissuprabasal cleft
spellingShingle Sukriti Arora
Raghavendra Rao
Pemphigus herpetiformis with atypical features
Clinical Dermatology Review
desmoglein 1 and 3 enzyme-linked immunosorbent assay
pemphigus herpetiformis
suprabasal cleft
title Pemphigus herpetiformis with atypical features
title_full Pemphigus herpetiformis with atypical features
title_fullStr Pemphigus herpetiformis with atypical features
title_full_unstemmed Pemphigus herpetiformis with atypical features
title_short Pemphigus herpetiformis with atypical features
title_sort pemphigus herpetiformis with atypical features
topic desmoglein 1 and 3 enzyme-linked immunosorbent assay
pemphigus herpetiformis
suprabasal cleft
url http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2022;volume=6;issue=2;spage=154;epage=154;aulast=Arora
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