Targeting netrin‐1/DCC interaction in diffuse large B‐cell and mantle cell lymphomas

Targeting netrin‐1/DCC interaction in diffuse large B‐cell and mantle cell lymphomas

Abstract DCC (Deleted in Colorectal Carcinoma) has been demonstrated to constrain tumor progression by inducing apoptosis unless engaged by its ligand netrin‐1. This has been shown in breast and colorectal cancers; however, this tumor suppressive function in other cancers is not established. Using a...

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Bibliographic Details
Main Authors: Laura Broutier, Marion Creveaux, Jonathan Vial, Antonin Tortereau, Jean‐Guy Delcros, Guillaume Chazot, Mark J McCarron, Sophie Léon, Céline Pangault, Nicolas Gadot, Amélie Colombe, Marie‐Laure Boulland, Jonathan Blachier, Julien C Marie, Alexandra Traverse‐Glehen, Olivier Donzé, Catherine Chassagne‐Clément, Gilles Salles, Karin Tarte, Patrick Mehlen, Marie Castets
Format: Article
Language:English
Published: Springer Nature 2016-02-01
Series:EMBO Molecular Medicine
Subjects:
apoptosis
dependence receptors
non‐Hodgkin lymphoma
DCC
netrin‐1
Online Access:https://doi.org/10.15252/emmm.201505480

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