Myocardial Glutathione Synthase and TRXIP Expression Are Significantly Elevated in Hypertension and Diabetes: Influence of Stress on Antioxidant Pathways

Myocardial Glutathione Synthase and TRXIP Expression Are Significantly Elevated in Hypertension and Diabetes: Influence of Stress on Antioxidant Pathways

Antioxidant protection is one of the key reactions of cardiomyocytes (CMCs) in response to myocardial damage of various origins. The thioredoxin interacting protein (TXNIP) is an inhibitor of thioredoxin (TXN). Over the recent few years, TXNIP has received significant attention due to its wide range...

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Bibliographic Details
Main Authors: Anastasia Sklifasovskaya, Mikhail Blagonravov, Madina Azova, Vyacheslav Goryachev
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pathophysiology
Subjects:
myocardial damage
thioredoxin interacting protein
glutathione synthetase
insulin-dependent diabetes mellitus
hypertension
Online Access:https://www.mdpi.com/1873-149X/30/2/21

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