Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future Therapies

Background Cancer remains a critical global health challenge and a leading cause of mortality. Flavonoids found in fruits and vegetables have gained attention for their potential anti-cancer properties. Fisetin, abundantly present in strawberries, apples, onions, and other plant sources,...

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Main Authors: Eskandar Qaed, Bandar Al-Hamyari, Ahmed Al-Maamari, Abdullah Qaid, Haneen Alademy, Marwan Almoiliqy, Jean Claude Munyemana, Murad Al-Nusaif, Jameel Alafifi, Eman Alyafeai, Mohammed Safi, Zhaohong Geng, Zeyao Tang, Xiaodong Ma
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2023-09-01
Series:Global Medical Genetics
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1772219
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author Eskandar Qaed
Bandar Al-Hamyari
Ahmed Al-Maamari
Abdullah Qaid
Haneen Alademy
Marwan Almoiliqy
Jean Claude Munyemana
Murad Al-Nusaif
Jameel Alafifi
Eman Alyafeai
Mohammed Safi
Zhaohong Geng
Zeyao Tang
Xiaodong Ma
author_facet Eskandar Qaed
Bandar Al-Hamyari
Ahmed Al-Maamari
Abdullah Qaid
Haneen Alademy
Marwan Almoiliqy
Jean Claude Munyemana
Murad Al-Nusaif
Jameel Alafifi
Eman Alyafeai
Mohammed Safi
Zhaohong Geng
Zeyao Tang
Xiaodong Ma
author_sort Eskandar Qaed
collection DOAJ
description Background Cancer remains a critical global health challenge and a leading cause of mortality. Flavonoids found in fruits and vegetables have gained attention for their potential anti-cancer properties. Fisetin, abundantly present in strawberries, apples, onions, and other plant sources, has emerged as a promising candidate for cancer prevention. Epidemiological studies linking a diet rich in these foods to lower cancer risk have sparked extensive research on fisetin’s efficacy.
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spelling doaj.art-544bc0640c0149989bdf0a748f784ba92023-08-09T23:06:50ZengGeorg Thieme Verlag KGGlobal Medical Genetics2699-94042023-09-01100320522010.1055/s-0043-1772219Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future TherapiesEskandar Qaed0Bandar Al-Hamyari1Ahmed Al-Maamari2Abdullah Qaid3Haneen Alademy4Marwan Almoiliqy5Jean Claude Munyemana6Murad Al-Nusaif7Jameel Alafifi8Eman Alyafeai9Mohammed Safi10Zhaohong Geng11Zeyao Tang12Xiaodong Ma13State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, People's Republic of ChinaSchool of Pharmacy and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, People's Republic of ChinaThe Key Laboratory of Neural and Vascular Biology, The Key Laboratory of New Drug Pharmacology and Toxicology, Department of Pharmacology, Ministry of Education, Hebei Medical University, Shijiazhuang, People's Republic of ChinaN.I. Pirogov Russian National Research Medical University, RussiaTaiz University Faculty of Medicine and Health Science, YemenDepartment of Pharmacy, Faculty of Medicine and Health Sciences, University of Science and Technology, Aden, YemenState Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, People's Republic of ChinaDepartment of Neurology and Liaoning Provincial Key Laboratory for Research on the Pathogenic Mechanisms of Neurological Diseases, the First Affiliated Hospital, Dalian Medical University, Dalian, People's Republic of ChinaSchool of Pharmacy and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, People's Republic of ChinaSchool of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, People's Republic of ChinaDepartment of Pharmacy, Dalian Medical University, Dalian, People's Republic of ChinaDepartment of Cardiology, 2nd Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of ChinaDepartment of Pharmacy, Dalian Medical University, Dalian, People's Republic of ChinaDepartment of Pharmacy, Dalian Medical University, Dalian, People's Republic of China Background Cancer remains a critical global health challenge and a leading cause of mortality. Flavonoids found in fruits and vegetables have gained attention for their potential anti-cancer properties. Fisetin, abundantly present in strawberries, apples, onions, and other plant sources, has emerged as a promising candidate for cancer prevention. Epidemiological studies linking a diet rich in these foods to lower cancer risk have sparked extensive research on fisetin’s efficacy.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1772219apoptosisautophagycell cycle arrestfisetin
spellingShingle Eskandar Qaed
Bandar Al-Hamyari
Ahmed Al-Maamari
Abdullah Qaid
Haneen Alademy
Marwan Almoiliqy
Jean Claude Munyemana
Murad Al-Nusaif
Jameel Alafifi
Eman Alyafeai
Mohammed Safi
Zhaohong Geng
Zeyao Tang
Xiaodong Ma
Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future Therapies
Global Medical Genetics
apoptosis
autophagy
cell cycle arrest
fisetin
title Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future Therapies
title_full Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future Therapies
title_fullStr Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future Therapies
title_full_unstemmed Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future Therapies
title_short Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future Therapies
title_sort fisetin s promising antitumor effects uncovering mechanisms and targeting for future therapies
topic apoptosis
autophagy
cell cycle arrest
fisetin
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1772219
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