Recombinantly Expressed Chimeric Fibers Demonstrate Discrete Type-Specific Neutralizing Epitopes in the Fowl Aviadenovirus E (FAdV-E) Fiber, Promoting the Optimization of FAdV Fiber Subunit Vaccines towards Cross-Protection in vivo
ABSTRACT Vaccines against inclusion body hepatitis in chickens are complicated by the involvement of antigenically diverse fowl adenovirus types. Though immunization with fiber protein confers robust protection, type specificity of fiber antibodies is an obstacle for the desired broad coverage. In t...
Asıl Yazarlar: | , , , |
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Materyal Türü: | Makale |
Dil: | English |
Baskı/Yayın Bilgisi: |
American Society for Microbiology
2022-02-01
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Seri Bilgileri: | Microbiology Spectrum |
Konular: | |
Online Erişim: | https://journals.asm.org/doi/10.1128/spectrum.02123-21 |