Towards unravelling biological mechanisms behind radiation-induced oral mucositis via mass spectrometry-based proteomics

Towards unravelling biological mechanisms behind radiation-induced oral mucositis via mass spectrometry-based proteomics

ObjectiveHead and neck cancer (HNC) accounts for almost 890,000 new cases per year. Radiotherapy (RT) is used to treat the majority of these patients. A common side-effect of RT is the onset of oral mucositis, which decreases the quality of life and represents the major dose-limiting factor in RT. T...

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Bibliographic Details
Main Authors: Prabal Subedi, Katharina Huber, Christoph Sterr, Anne Dietz, Lukas Strasser, Felix Kaestle, Stefanie M. Hauck, Lukas Duchrow, Christine Aldrian, Elsa Beatriz Monroy Ordonez, Benedikt Luka, Andreas R. Thomsen, Michael Henke, Maria Gomolka, Ute Rößler, Omid Azimzadeh, Simone Moertl, Sabine Hornhardt
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
radiotherapy
keratinocytes
biomarker
mass spectrometry-based proteomics
interferon response
STAT phosphorylation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1180642/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1180642/full

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