Explainable DCNN based chest X-ray image analysis and classification for COVID-19 pneumonia detection

Abstract To speed up the discovery of COVID-19 disease mechanisms by X-ray images, this research developed a new diagnosis platform using a deep convolutional neural network (DCNN) that is able to assist radiologists with diagnosis by distinguishing COVID-19 pneumonia from non-COVID-19 pneumonia in...

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Main Authors: Jie Hou, Terry Gao
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95680-6
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author Jie Hou
Terry Gao
author_facet Jie Hou
Terry Gao
author_sort Jie Hou
collection DOAJ
description Abstract To speed up the discovery of COVID-19 disease mechanisms by X-ray images, this research developed a new diagnosis platform using a deep convolutional neural network (DCNN) that is able to assist radiologists with diagnosis by distinguishing COVID-19 pneumonia from non-COVID-19 pneumonia in patients based on chest X-ray classification and analysis. Such a tool can save time in interpreting chest X-rays and increase the accuracy and thereby enhance our medical capacity for the detection and diagnosis of COVID-19. The explainable method is also used in the DCNN to select instances of the X-ray dataset images to explain the behavior of training-learning models to achieve higher prediction accuracy. The average accuracy of our method is above 96%, which can replace manual reading and has the potential to be applied to large-scale rapid screening of COVID-9 for widely use cases.
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spelling doaj.art-545602688df14dda9eb1eb3571c562bd2022-12-21T18:01:41ZengNature PortfolioScientific Reports2045-23222021-08-0111111510.1038/s41598-021-95680-6Explainable DCNN based chest X-ray image analysis and classification for COVID-19 pneumonia detectionJie Hou0Terry Gao1School of Biomedical Engineering, Guangdong Medical UniversityCounties Manukau District Health BoardAbstract To speed up the discovery of COVID-19 disease mechanisms by X-ray images, this research developed a new diagnosis platform using a deep convolutional neural network (DCNN) that is able to assist radiologists with diagnosis by distinguishing COVID-19 pneumonia from non-COVID-19 pneumonia in patients based on chest X-ray classification and analysis. Such a tool can save time in interpreting chest X-rays and increase the accuracy and thereby enhance our medical capacity for the detection and diagnosis of COVID-19. The explainable method is also used in the DCNN to select instances of the X-ray dataset images to explain the behavior of training-learning models to achieve higher prediction accuracy. The average accuracy of our method is above 96%, which can replace manual reading and has the potential to be applied to large-scale rapid screening of COVID-9 for widely use cases.https://doi.org/10.1038/s41598-021-95680-6
spellingShingle Jie Hou
Terry Gao
Explainable DCNN based chest X-ray image analysis and classification for COVID-19 pneumonia detection
Scientific Reports
title Explainable DCNN based chest X-ray image analysis and classification for COVID-19 pneumonia detection
title_full Explainable DCNN based chest X-ray image analysis and classification for COVID-19 pneumonia detection
title_fullStr Explainable DCNN based chest X-ray image analysis and classification for COVID-19 pneumonia detection
title_full_unstemmed Explainable DCNN based chest X-ray image analysis and classification for COVID-19 pneumonia detection
title_short Explainable DCNN based chest X-ray image analysis and classification for COVID-19 pneumonia detection
title_sort explainable dcnn based chest x ray image analysis and classification for covid 19 pneumonia detection
url https://doi.org/10.1038/s41598-021-95680-6
work_keys_str_mv AT jiehou explainabledcnnbasedchestxrayimageanalysisandclassificationforcovid19pneumoniadetection
AT terrygao explainabledcnnbasedchestxrayimageanalysisandclassificationforcovid19pneumoniadetection