The effectiveness of vitamin D supplementation in functional outcome and quality of life (QoL) of lumbar spinal stenosis (LSS) requiring surgery
Abstract Study design This is a retrospective cohort comparative study. Background Vitamin D supplementation is considered to be associated with good functional outcome. Thus, a few studies have proposed vitamin D supplementation is benefit to the functional outcome in LSS requiring surgery. The pur...
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| Format: | Article |
| Language: | English |
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BMC
2020-03-01
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| Series: | Journal of Orthopaedic Surgery and Research |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13018-020-01629-2 |
| _version_ | 1811264264477868032 |
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| author | Sangbong Ko Seungbum Chae Wonkee Choi Jaibum Kwon Je-Yong Choi |
| author_facet | Sangbong Ko Seungbum Chae Wonkee Choi Jaibum Kwon Je-Yong Choi |
| author_sort | Sangbong Ko |
| collection | DOAJ |
| description | Abstract Study design This is a retrospective cohort comparative study. Background Vitamin D supplementation is considered to be associated with good functional outcome. Thus, a few studies have proposed vitamin D supplementation is benefit to the functional outcome in LSS requiring surgery. The purpose of this study is to identify the prevalence of vitamin D deficiency in patients with LSS requiring surgery, and to compare the differences between the cases whether vitamin D is supplemented and vitamin D is not supplemented in terms of a QoL during postoperative 2 year. Methods All patients with LSS who underwent surgery from March 1, 2015 to August 31, 2016 were enrolled. Among them, 61 patients with vitamin D deficiency were divided into two groups (supplemented group (A) and non-supplemented group (B)). Functional outcomes using Oswestry Disability Index (ODI) and Rolland Morris Disability Index (RMDQ) and QoL using SF-36 were evaluated at 12-month and 24-month follow-up periods. Differences in functional score and SF-36 between the vitamin D supplemented and non-supplemented group were compared. Results Among the total 102 patients, 78 patients (76.5%) had vitamin D deficiency. Of the 78 patients, 61 patients were included, 27 patients were group A and 27 patients were group B. There was no difference in age and 25-OHD level between the two groups (all 0 > 0.05). Group A were better functional outcomes at 2 years after surgery (p < 0.05). On the QoL, group A were higher score than group B from 12 month later after surgery (p < 0.05). Conclusions Vitamin D deficiency was highly prevalent in LSS patients (76.5%). Assessment of serum 25-hydroxyvitamin D (25(OH)D) is recommended in LSS needing surgical intervention and active treatment vitamin D supplementation and maintenance of normal range should be considered for better postoperative functional outcome and QoL. |
| first_indexed | 2024-04-12T20:01:02Z |
| format | Article |
| id | doaj.art-54594fa3eeae490f8a82f7c0f20611e6 |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-04-12T20:01:02Z |
| publishDate | 2020-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-54594fa3eeae490f8a82f7c0f20611e62022-12-22T03:18:32ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2020-03-011511610.1186/s13018-020-01629-2The effectiveness of vitamin D supplementation in functional outcome and quality of life (QoL) of lumbar spinal stenosis (LSS) requiring surgerySangbong Ko0Seungbum Chae1Wonkee Choi2Jaibum Kwon3Je-Yong Choi4Department of Orthopaedic Surgery, College of Medicine, Daegu Catholic UniversityDepartment of Orthopaedic Surgery, College of Medicine, Daegu Catholic UniversityDepartment of Orthopaedic Surgery, College of Medicine, Daegu Catholic UniversityDepartment of Orthopaedic Surgery, College of Medicine, Daegu Catholic UniversityDepartment of Biochemistry and Cell Biology, Kyungpook National UniversityAbstract Study design This is a retrospective cohort comparative study. Background Vitamin D supplementation is considered to be associated with good functional outcome. Thus, a few studies have proposed vitamin D supplementation is benefit to the functional outcome in LSS requiring surgery. The purpose of this study is to identify the prevalence of vitamin D deficiency in patients with LSS requiring surgery, and to compare the differences between the cases whether vitamin D is supplemented and vitamin D is not supplemented in terms of a QoL during postoperative 2 year. Methods All patients with LSS who underwent surgery from March 1, 2015 to August 31, 2016 were enrolled. Among them, 61 patients with vitamin D deficiency were divided into two groups (supplemented group (A) and non-supplemented group (B)). Functional outcomes using Oswestry Disability Index (ODI) and Rolland Morris Disability Index (RMDQ) and QoL using SF-36 were evaluated at 12-month and 24-month follow-up periods. Differences in functional score and SF-36 between the vitamin D supplemented and non-supplemented group were compared. Results Among the total 102 patients, 78 patients (76.5%) had vitamin D deficiency. Of the 78 patients, 61 patients were included, 27 patients were group A and 27 patients were group B. There was no difference in age and 25-OHD level between the two groups (all 0 > 0.05). Group A were better functional outcomes at 2 years after surgery (p < 0.05). On the QoL, group A were higher score than group B from 12 month later after surgery (p < 0.05). Conclusions Vitamin D deficiency was highly prevalent in LSS patients (76.5%). Assessment of serum 25-hydroxyvitamin D (25(OH)D) is recommended in LSS needing surgical intervention and active treatment vitamin D supplementation and maintenance of normal range should be considered for better postoperative functional outcome and QoL.http://link.springer.com/article/10.1186/s13018-020-01629-2Lumbar spineSpinal StenosisSurgeryVitamin DFunctional OutcomeQuality of Life |
| spellingShingle | Sangbong Ko Seungbum Chae Wonkee Choi Jaibum Kwon Je-Yong Choi The effectiveness of vitamin D supplementation in functional outcome and quality of life (QoL) of lumbar spinal stenosis (LSS) requiring surgery Journal of Orthopaedic Surgery and Research Lumbar spine Spinal Stenosis Surgery Vitamin D Functional Outcome Quality of Life |
| title | The effectiveness of vitamin D supplementation in functional outcome and quality of life (QoL) of lumbar spinal stenosis (LSS) requiring surgery |
| title_full | The effectiveness of vitamin D supplementation in functional outcome and quality of life (QoL) of lumbar spinal stenosis (LSS) requiring surgery |
| title_fullStr | The effectiveness of vitamin D supplementation in functional outcome and quality of life (QoL) of lumbar spinal stenosis (LSS) requiring surgery |
| title_full_unstemmed | The effectiveness of vitamin D supplementation in functional outcome and quality of life (QoL) of lumbar spinal stenosis (LSS) requiring surgery |
| title_short | The effectiveness of vitamin D supplementation in functional outcome and quality of life (QoL) of lumbar spinal stenosis (LSS) requiring surgery |
| title_sort | effectiveness of vitamin d supplementation in functional outcome and quality of life qol of lumbar spinal stenosis lss requiring surgery |
| topic | Lumbar spine Spinal Stenosis Surgery Vitamin D Functional Outcome Quality of Life |
| url | http://link.springer.com/article/10.1186/s13018-020-01629-2 |
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