Anti-Aging Effects of a Serum Based on Coconut Oil Combined with Deer Antler Stem Cell Extract on a Mouse Model of Skin Aging
Anti-aging is one of the top goals in the field of health care and aesthetics. Anti-aging cosmetics derived from nature are oriented to long-term development, bringing safety to users and being environmentally friendly. The aim of this study was to develop an anti-aging cosmetic formulation process...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/11/4/597 |
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| author | Truc Le-Buu Pham Thuy Truong Thi Huyen Thi-Thuong Nguyen Thuan Duc Lao Nguyen Trong Binh Quan Dang Nguyen |
| author_facet | Truc Le-Buu Pham Thuy Truong Thi Huyen Thi-Thuong Nguyen Thuan Duc Lao Nguyen Trong Binh Quan Dang Nguyen |
| author_sort | Truc Le-Buu Pham |
| collection | DOAJ |
| description | Anti-aging is one of the top goals in the field of health care and aesthetics. Anti-aging cosmetics derived from nature are oriented to long-term development, bringing safety to users and being environmentally friendly. The aim of this study was to develop an anti-aging cosmetic formulation process based on coconut oil in combination with deer antler stem cell extract. The results show that the presence of deer antler stem cell extract added to the foundation made the serum product highly stable and helped improve skin aging significantly after 2 weeks of use. The skin site where the serum product was applied showed a smooth and elastic skin surface, with very few fine lines and shallow wrinkles. Serum reduced the number of wrinkles (48.09% compared to commercial serum (ME) and 60.31% compared to positive control (PC)), reduced skin recovery time (39.31% compared to ME and 67.1% of PC) after two weeks of use. After 2 weeks of use, collagen density increased 10.18% compared to ME and 63.76% compared to control. Epidermal thickness increased by 106.1% compared to PC and 121.7% compared to ME. |
| first_indexed | 2024-03-09T22:21:05Z |
| format | Article |
| id | doaj.art-5459be7450b9453c8d168fe4d1f1a867 |
| institution | Directory Open Access Journal |
| issn | 2073-4409 |
| language | English |
| last_indexed | 2024-03-09T22:21:05Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj.art-5459be7450b9453c8d168fe4d1f1a8672023-11-23T19:13:51ZengMDPI AGCells2073-44092022-02-0111459710.3390/cells11040597Anti-Aging Effects of a Serum Based on Coconut Oil Combined with Deer Antler Stem Cell Extract on a Mouse Model of Skin AgingTruc Le-Buu Pham0Thuy Truong Thi1Huyen Thi-Thuong Nguyen2Thuan Duc Lao3Nguyen Trong Binh4Quan Dang Nguyen5Department of Animal Biotechnology, Biotechnology Center of Ho Chi Minh City, Ho Chi Minh City 700000, VietnamDepartment of Animal Biotechnology, Biotechnology Center of Ho Chi Minh City, Ho Chi Minh City 700000, VietnamDepartment of Biology, Ho Chi Minh City University of Education, Ho Chi Minh City 700000, VietnamFaculty of Biotechnology, Ho Chi Minh City Open University, Ho Chi Minh City 700000, VietnamDepartment of Animal Biotechnology, Biotechnology Center of Ho Chi Minh City, Ho Chi Minh City 700000, VietnamDepartment of Animal Biotechnology, Biotechnology Center of Ho Chi Minh City, Ho Chi Minh City 700000, VietnamAnti-aging is one of the top goals in the field of health care and aesthetics. Anti-aging cosmetics derived from nature are oriented to long-term development, bringing safety to users and being environmentally friendly. The aim of this study was to develop an anti-aging cosmetic formulation process based on coconut oil in combination with deer antler stem cell extract. The results show that the presence of deer antler stem cell extract added to the foundation made the serum product highly stable and helped improve skin aging significantly after 2 weeks of use. The skin site where the serum product was applied showed a smooth and elastic skin surface, with very few fine lines and shallow wrinkles. Serum reduced the number of wrinkles (48.09% compared to commercial serum (ME) and 60.31% compared to positive control (PC)), reduced skin recovery time (39.31% compared to ME and 67.1% of PC) after two weeks of use. After 2 weeks of use, collagen density increased 10.18% compared to ME and 63.76% compared to control. Epidermal thickness increased by 106.1% compared to PC and 121.7% compared to ME.https://www.mdpi.com/2073-4409/11/4/597deer antler stem cellsmouseultraviolet A (UVA)virgin coconut oil (VCO) |
| spellingShingle | Truc Le-Buu Pham Thuy Truong Thi Huyen Thi-Thuong Nguyen Thuan Duc Lao Nguyen Trong Binh Quan Dang Nguyen Anti-Aging Effects of a Serum Based on Coconut Oil Combined with Deer Antler Stem Cell Extract on a Mouse Model of Skin Aging Cells deer antler stem cells mouse ultraviolet A (UVA) virgin coconut oil (VCO) |
| title | Anti-Aging Effects of a Serum Based on Coconut Oil Combined with Deer Antler Stem Cell Extract on a Mouse Model of Skin Aging |
| title_full | Anti-Aging Effects of a Serum Based on Coconut Oil Combined with Deer Antler Stem Cell Extract on a Mouse Model of Skin Aging |
| title_fullStr | Anti-Aging Effects of a Serum Based on Coconut Oil Combined with Deer Antler Stem Cell Extract on a Mouse Model of Skin Aging |
| title_full_unstemmed | Anti-Aging Effects of a Serum Based on Coconut Oil Combined with Deer Antler Stem Cell Extract on a Mouse Model of Skin Aging |
| title_short | Anti-Aging Effects of a Serum Based on Coconut Oil Combined with Deer Antler Stem Cell Extract on a Mouse Model of Skin Aging |
| title_sort | anti aging effects of a serum based on coconut oil combined with deer antler stem cell extract on a mouse model of skin aging |
| topic | deer antler stem cells mouse ultraviolet A (UVA) virgin coconut oil (VCO) |
| url | https://www.mdpi.com/2073-4409/11/4/597 |
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