Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance
Abstract Background The incidence of Escherichia coli bloodstream infections (BSI) is high and increasing. We aimed to describe the effect of season and temperature on the incidence of E. coli BSI and antibiotic-resistant E. coli BSI and to determine differences by place of BSI onset. Methods All E....
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| Format: | Article |
| Language: | English |
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BMC
2022-11-01
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| Series: | Antimicrobial Resistance and Infection Control |
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| Online Access: | https://doi.org/10.1186/s13756-022-01184-x |
| _version_ | 1811187003930181632 |
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| author | Sarah F. Feldman Elizabeth Temkin Liat Wulffhart Amir Nutman Vered Schechner Pnina Shitrit Racheli Shvartz Mitchell J. Schwaber Yehuda Carmeli |
| author_facet | Sarah F. Feldman Elizabeth Temkin Liat Wulffhart Amir Nutman Vered Schechner Pnina Shitrit Racheli Shvartz Mitchell J. Schwaber Yehuda Carmeli |
| author_sort | Sarah F. Feldman |
| collection | DOAJ |
| description | Abstract Background The incidence of Escherichia coli bloodstream infections (BSI) is high and increasing. We aimed to describe the effect of season and temperature on the incidence of E. coli BSI and antibiotic-resistant E. coli BSI and to determine differences by place of BSI onset. Methods All E. coli BSI in adult Israeli residents between January 1, 2018 and December 19, 2019 were included. We used the national database of mandatory BSI reports and outdoor temperature data. Monthly incidence and resistance were studied using multivariable negative binomial regressions with season (July–October vs. other) and temperature as covariates. Results We included 10,583 events, 9012 (85%) community onset (CO) and 1571 (15%) hospital onset (HO). For CO events, for each average monthly temperature increase of 5.5 °C, the monthly number of events increased by 6.2% (95% CI 1.6–11.1%, p = 0.008) and the monthly number of multidrug-resistant events increased by 4.9% (95% CI 0.3–9.7%, p = 0.04). The effect of season was not significant. For HO events, incidence of BSI and resistant BSI were not associated with temperature or season. Conclusion Temperature increases the incidence of CO E. coli BSI and CO antibiotic-resistant E. coli BSI. Global warming threatens to increase the incidence of E. coli BSI. |
| first_indexed | 2024-04-11T13:54:52Z |
| format | Article |
| id | doaj.art-545dc00a5cf24941b9134e346f6123bd |
| institution | Directory Open Access Journal |
| issn | 2047-2994 |
| language | English |
| last_indexed | 2024-04-11T13:54:52Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Antimicrobial Resistance and Infection Control |
| spelling | doaj.art-545dc00a5cf24941b9134e346f6123bd2022-12-22T04:20:22ZengBMCAntimicrobial Resistance and Infection Control2047-29942022-11-011111910.1186/s13756-022-01184-xEffect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistanceSarah F. Feldman0Elizabeth Temkin1Liat Wulffhart2Amir Nutman3Vered Schechner4Pnina Shitrit5Racheli Shvartz6Mitchell J. Schwaber7Yehuda Carmeli8National Institute for Antibiotic Resistance and Infection Control, Ministry of HealthNational Institute for Antibiotic Resistance and Infection Control, Ministry of HealthNational Institute for Antibiotic Resistance and Infection Control, Ministry of HealthNational Institute for Antibiotic Resistance and Infection Control, Ministry of HealthNational Institute for Antibiotic Resistance and Infection Control, Ministry of HealthSackler Faculty of Medicine, Tel Aviv UniversityNational Institute for Antibiotic Resistance and Infection Control, Ministry of HealthNational Institute for Antibiotic Resistance and Infection Control, Ministry of HealthNational Institute for Antibiotic Resistance and Infection Control, Ministry of HealthAbstract Background The incidence of Escherichia coli bloodstream infections (BSI) is high and increasing. We aimed to describe the effect of season and temperature on the incidence of E. coli BSI and antibiotic-resistant E. coli BSI and to determine differences by place of BSI onset. Methods All E. coli BSI in adult Israeli residents between January 1, 2018 and December 19, 2019 were included. We used the national database of mandatory BSI reports and outdoor temperature data. Monthly incidence and resistance were studied using multivariable negative binomial regressions with season (July–October vs. other) and temperature as covariates. Results We included 10,583 events, 9012 (85%) community onset (CO) and 1571 (15%) hospital onset (HO). For CO events, for each average monthly temperature increase of 5.5 °C, the monthly number of events increased by 6.2% (95% CI 1.6–11.1%, p = 0.008) and the monthly number of multidrug-resistant events increased by 4.9% (95% CI 0.3–9.7%, p = 0.04). The effect of season was not significant. For HO events, incidence of BSI and resistant BSI were not associated with temperature or season. Conclusion Temperature increases the incidence of CO E. coli BSI and CO antibiotic-resistant E. coli BSI. Global warming threatens to increase the incidence of E. coli BSI.https://doi.org/10.1186/s13756-022-01184-xEscherichia coliBloodstream infectionAntibiotic resistanceEpidemiologyTemperatureSeasonal variation |
| spellingShingle | Sarah F. Feldman Elizabeth Temkin Liat Wulffhart Amir Nutman Vered Schechner Pnina Shitrit Racheli Shvartz Mitchell J. Schwaber Yehuda Carmeli Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance Antimicrobial Resistance and Infection Control Escherichia coli Bloodstream infection Antibiotic resistance Epidemiology Temperature Seasonal variation |
| title | Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance |
| title_full | Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance |
| title_fullStr | Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance |
| title_full_unstemmed | Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance |
| title_short | Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance |
| title_sort | effect of temperature on escherichia coli bloodstream infection in a nationwide population based study of incidence and resistance |
| topic | Escherichia coli Bloodstream infection Antibiotic resistance Epidemiology Temperature Seasonal variation |
| url | https://doi.org/10.1186/s13756-022-01184-x |
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