Solvothermal Synthesis of Calcium Hydroxyapatite via Hydrolysis of Alpha-Tricalcium Phosphate in the Presence of Different Organic Additives
In this study, the effects of sodium lauryl sulfate and various amino acids (DL-aspartic acid, dodecanedioic acid, and suberic acid) on the formation of calcium-deficient hydroxyapatite via hydrolysis of α-tricalcium phosphate (α-TCP) were investigated; moreover, a combined effect of these additives...
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MDPI AG
2023-02-01
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| Series: | Crystals |
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| Online Access: | https://www.mdpi.com/2073-4352/13/2/265 |
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| author | Rasa Karalkeviciene Eva Raudonyte-Svirbutaviciene Aleksej Zarkov Jen-Chang Yang Anatoli I. Popov Aivaras Kareiva |
| author_facet | Rasa Karalkeviciene Eva Raudonyte-Svirbutaviciene Aleksej Zarkov Jen-Chang Yang Anatoli I. Popov Aivaras Kareiva |
| author_sort | Rasa Karalkeviciene |
| collection | DOAJ |
| description | In this study, the effects of sodium lauryl sulfate and various amino acids (DL-aspartic acid, dodecanedioic acid, and suberic acid) on the formation of calcium-deficient hydroxyapatite via hydrolysis of α-tricalcium phosphate (α-TCP) were investigated; moreover, a combined effect of these additives and ethylene glycol as a synthesis medium was also estimated. The hydrolysis reaction was performed in solutions containing different concentrations of additives in aqueous and mixed aqueous–organic media under solvothermal conditions. It was demonstrated that the nature and the concentration of organic additives influence the phase purity and morphology of the final product. Higher concentrations of sodium lauryl sulfate and dodecanedioic acid induced the formation of impurities in addition to hydroxyapatite, while aspartic and suberic acid did not affect the phase purity. The morphology of the samples varied from plate- to rod-like depending on the concentrations of specific organic additive. |
| first_indexed | 2024-03-11T08:57:50Z |
| format | Article |
| id | doaj.art-54637f8714a74cfaa510609773af7f3b |
| institution | Directory Open Access Journal |
| issn | 2073-4352 |
| language | English |
| last_indexed | 2024-03-11T08:57:50Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Crystals |
| spelling | doaj.art-54637f8714a74cfaa510609773af7f3b2023-11-16T19:55:49ZengMDPI AGCrystals2073-43522023-02-0113226510.3390/cryst13020265Solvothermal Synthesis of Calcium Hydroxyapatite via Hydrolysis of Alpha-Tricalcium Phosphate in the Presence of Different Organic AdditivesRasa Karalkeviciene0Eva Raudonyte-Svirbutaviciene1Aleksej Zarkov2Jen-Chang Yang3Anatoli I. Popov4Aivaras Kareiva5Institute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko 24, LT-03225 Vilnius, LithuaniaInstitute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko 24, LT-03225 Vilnius, LithuaniaInstitute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko 24, LT-03225 Vilnius, LithuaniaGraduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, 250 Wu-Hsing St., Taipei 11052, TaiwanInstitute of Solid State Physics, University of Latvia, Kengaraga 8, LV-1063 Riga, LatviaInstitute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko 24, LT-03225 Vilnius, LithuaniaIn this study, the effects of sodium lauryl sulfate and various amino acids (DL-aspartic acid, dodecanedioic acid, and suberic acid) on the formation of calcium-deficient hydroxyapatite via hydrolysis of α-tricalcium phosphate (α-TCP) were investigated; moreover, a combined effect of these additives and ethylene glycol as a synthesis medium was also estimated. The hydrolysis reaction was performed in solutions containing different concentrations of additives in aqueous and mixed aqueous–organic media under solvothermal conditions. It was demonstrated that the nature and the concentration of organic additives influence the phase purity and morphology of the final product. Higher concentrations of sodium lauryl sulfate and dodecanedioic acid induced the formation of impurities in addition to hydroxyapatite, while aspartic and suberic acid did not affect the phase purity. The morphology of the samples varied from plate- to rod-like depending on the concentrations of specific organic additive.https://www.mdpi.com/2073-4352/13/2/265calcium hydroxyapatiteα-tricalcium phosphateamino acidsorganic additivessolvothermal synthesis |
| spellingShingle | Rasa Karalkeviciene Eva Raudonyte-Svirbutaviciene Aleksej Zarkov Jen-Chang Yang Anatoli I. Popov Aivaras Kareiva Solvothermal Synthesis of Calcium Hydroxyapatite via Hydrolysis of Alpha-Tricalcium Phosphate in the Presence of Different Organic Additives Crystals calcium hydroxyapatite α-tricalcium phosphate amino acids organic additives solvothermal synthesis |
| title | Solvothermal Synthesis of Calcium Hydroxyapatite via Hydrolysis of Alpha-Tricalcium Phosphate in the Presence of Different Organic Additives |
| title_full | Solvothermal Synthesis of Calcium Hydroxyapatite via Hydrolysis of Alpha-Tricalcium Phosphate in the Presence of Different Organic Additives |
| title_fullStr | Solvothermal Synthesis of Calcium Hydroxyapatite via Hydrolysis of Alpha-Tricalcium Phosphate in the Presence of Different Organic Additives |
| title_full_unstemmed | Solvothermal Synthesis of Calcium Hydroxyapatite via Hydrolysis of Alpha-Tricalcium Phosphate in the Presence of Different Organic Additives |
| title_short | Solvothermal Synthesis of Calcium Hydroxyapatite via Hydrolysis of Alpha-Tricalcium Phosphate in the Presence of Different Organic Additives |
| title_sort | solvothermal synthesis of calcium hydroxyapatite via hydrolysis of alpha tricalcium phosphate in the presence of different organic additives |
| topic | calcium hydroxyapatite α-tricalcium phosphate amino acids organic additives solvothermal synthesis |
| url | https://www.mdpi.com/2073-4352/13/2/265 |
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