Drug Resistance in Cancers: A Free Pass for Bullying

Drug Resistance in Cancers: A Free Pass for Bullying

The cancer burden continues to grow globally, and drug resistance remains a substantial challenge in cancer therapy. It is well established that cancerous cells with clonal dysplasia generate the same carcinogenic lesions. Tumor cells pass on genetic templates to subsequent generations in evolutiona...

Full description

Bibliographic Details
Main Authors:	Jing Li, Xiao Li, Qie Guo
Format:	Article
Language:	English
Published:	MDPI AG 2022-10-01
Series:	Cells
Subjects:	drug resistance tumor microenvironment exosomes metabolic reprogramming glycosylation autophagy
Online Access:	https://www.mdpi.com/2073-4409/11/21/3383

Similar Items

Secretory Autophagy Forges a Therapy Resistant Microenvironment in Melanoma
by: Silvina Odete Bustos, et al.
Published: (2022-01-01)

Drug Resistance: The Role of Exosomal miRNA in the Microenvironment of Hematopoietic Tumors
by: Mariaconcetta Cariello, et al.
Published: (2022-12-01)

Little things with significant impact: miRNAs in hepatocellular carcinoma
by: Jiehan Li, et al.
Published: (2023-05-01)

Novel strategy for oncogenic alteration-induced lipid metabolism reprogramming in pancreatic cancer
by: Guo Duancheng, et al.
Published: (2023-04-01)

Exosome derived from tumor-associated macrophages: biogenesis, functions, and therapeutic implications in human cancers
by: Manli Zhou, et al.
Published: (2023-11-01)

Hypoxia, Metabolic Reprogramming, and Drug Resistance in Liver Cancer
by: Macus Hao-Ran Bao, et al.
Published: (2021-07-01)

The crosstalk within the breast tumor microenvironment in type II diabetes: Implications for cancer disparities
by: Christina S. Ennis, et al.
Published: (2022-12-01)

Molecular and cellular paradigms of multidrug resistance in cancer
by: Foram U. Vaidya, et al.
Published: (2022-12-01)

Mechanisms of drug resistance in breast cancer liver metastases: Dilemmas and opportunities
by: Chun-Yan Yan, et al.
Published: (2023-03-01)

Metabolic reprogramming, autophagy, and ferroptosis: Novel arsenals to overcome immunotherapy resistance in gastrointestinal cancer
by: Xiangwen Wang, et al.
Published: (2023-11-01)

Metabolic Reprogramming in Tumor Endothelial Cells
by: Melissa García-Caballero, et al.
Published: (2022-09-01)

Harnessing Metabolic Reprogramming to Improve Cancer Immunotherapy
by: Liang Yan, et al.
Published: (2021-09-01)

A glycosylation-related gene signature predicts prognosis, immune microenvironment infiltration, and drug sensitivity in glioma
by: Yanbo Yang, et al.
Published: (2024-01-01)

Nanomedicines Targeting Metabolism in the Tumor Microenvironment
by: Mengdi Ren, et al.
Published: (2022-08-01)

Metabolic reprogramming of the tumor immune microenvironment in ovarian cancer: A novel orientation for immunotherapy
by: Yi Lin, et al.
Published: (2022-10-01)

Advances in macrophage and T cell metabolic reprogramming and immunotherapy in the tumor microenvironment
by: Hua Cheng, et al.
Published: (2024-01-01)

ANXA6: a key molecular player in cancer progression and drug resistance
by: Jinlong Cao, et al.
Published: (2023-05-01)

Relationship between metabolic reprogramming and drug resistance in breast cancer
by: Linlin Lv, et al.
Published: (2022-08-01)

Targeting lipid metabolism reprogramming of immunocytes in response to the tumor microenvironment stressor: A potential approach for tumor therapy
by: Ming Zhang, et al.
Published: (2022-09-01)

Surface Engineering of HEK293 Cell-Derived Extracellular Vesicles for Improved Pharmacokinetic Profile and Targeted Delivery of IL-12 for the Treatment of Hepatocellular Carcinoma
by: Zhang J, et al.
Published: (2023-01-01)

The roles of epigallocatechin gallate in the tumor microenvironment, metabolic reprogramming, and immunotherapy
by: Dongming Li, et al.
Published: (2024-01-01)

The potential of aryl hydrocarbon receptor as receptors for metabolic changes in tumors
by: Zhiying Wang, et al.
Published: (2024-02-01)

Metabolic Reprogramming in Cancer Cells: Emerging Molecular Mechanisms and Novel Therapeutic Approaches
by: Carla Navarro, et al.
Published: (2022-06-01)

A role for platelets in metabolic reprogramming of tumor-associated macrophages
by: Ying Kang, et al.
Published: (2023-08-01)

Recent Insights into Mechanisms Governing Breast Cancer Dormancy
by: MA Lanjing, et al.
Published: (2023-12-01)

Metabolic Classification and Intervention Opportunities for Tumor Energy Dysfunction
by: Ezequiel Monferrer, et al.
Published: (2021-04-01)

New Immunometabolic Strategy Based on Cell Type-Specific Metabolic Reprogramming in the Tumor Immune Microenvironment
by: Ji-Yong Sung, et al.
Published: (2022-02-01)

Amino acid metabolism reprogramming: shedding new light on T cell anti-tumor immunity
by: Yue Zheng, et al.
Published: (2023-11-01)

Small extracellular vesicle-mediated metabolic reprogramming: from tumors to pre-metastatic niche formation
by: Chuwen Jiang, et al.
Published: (2023-05-01)

Non-coding RNAs in metabolic reprogramming of bone and soft tissue sarcoma: Fundamental mechanism and clinical implication
by: Huan-Huan Chen, et al.
Published: (2023-04-01)

NAD/NAMPT and mTOR Pathways in Melanoma: Drivers of Drug Resistance and Prospective Therapeutic Targets
by: Alice Indini, et al.
Published: (2022-09-01)

Dual effects of radiotherapy on tumor microenvironment and its contribution towards the development of resistance to immunotherapy in gastrointestinal and thoracic cancers
by: Deyao Zhao, et al.
Published: (2023-10-01)

The Illustration of Altered Glucose Dependency in Drug-Resistant Cancer Cells
by: Kausik Bishayee, et al.
Published: (2023-09-01)

CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling
by: Chen Ai, et al.
Published: (2023-07-01)

Targeting T-cell metabolism to boost immune checkpoint inhibitor therapy
by: Haohao Li, et al.
Published: (2022-12-01)

Lipid Metabolism Heterogeneity and Crosstalk with Mitochondria Functions Drive Breast Cancer Progression and Drug Resistance
by: Aurelien Azam, et al.
Published: (2022-12-01)

The roles and mechanisms of SREBP1 in cancer development and drug response
by: Ying He, et al.
Published: (2024-07-01)

The role of autophagy in regulating metabolism in the tumor microenvironment
by: Panpan Zhang, et al.
Published: (2023-03-01)

The role of tumor microenvironment reprogramming in primary liver cancer chemotherapy resistance
by: Chunyu Zhao, et al.
Published: (2022-11-01)

The critical role of the tumor microenvironment in shaping natural killer cell-mediated anti-tumor immunity
by: Joanna eBaginska, et al.
Published: (2013-12-01)