Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum Infections.

Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum Infections.

Virulence of the most deadly malaria parasite Plasmodium falciparum is linked to the variant surface antigen PfEMP1, which is encoded by about 60 var genes per parasite genome. Although the expression of particular variants has been associated with different clinical outcomes, little is known about...

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Bibliografische gegevens
Hoofdauteurs: Anna Bachmann, Michaela Petter, Ralf Krumkamp, Meral Esen, Jana Held, Judith A M Scholz, Tao Li, B Kim Lee Sim, Stephen L Hoffman, Peter G Kremsner, Benjamin Mordmüller, Michael F Duffy, Egbert Tannich
Formaat: Artikel
Taal:English
Gepubliceerd in: Public Library of Science (PLoS) 2016-04-01
Reeks:PLoS Pathogens
Online toegang:https://doi.org/10.1371/journal.ppat.1005538

Internet

https://doi.org/10.1371/journal.ppat.1005538

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