Chlorogenic Acid Attenuates Oxidative Stress-Induced Intestinal Epithelium Injury by Co-Regulating the PI3K/Akt and IκBα/NF-κB Signaling

Chlorogenic Acid Attenuates Oxidative Stress-Induced Intestinal Epithelium Injury by Co-Regulating the PI3K/Akt and IκBα/NF-κB Signaling

Chlorogenic acid (CGA) is a natural polyphenol compound abundant in green plants with antioxidant and anti-inflammatory activities. Here, we explore its protective effects and potential mechanisms of action on intestinal epithelium exposure to oxidative stress (OS). We show that CGA attenuated OS-in...

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Bibliographic Details
Main Authors: Jiali Chen, Yuheng Luo, Yan Li, Daiwen Chen, Bing Yu, Jun He
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Antioxidants
Subjects:
chlorogenic acid
weaned pigs
intestinal epithelial cells
oxidative stress
inflammation
signaling pathway
Online Access:https://www.mdpi.com/2076-3921/10/12/1915

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