Severe adverse reactions after cyanoacrylate endovenous ablation

Hypersensitivity reactions after endovenous ablation with cyanoacrylate are relatively common, mild, and self-limited. However, rare cases of severe hypersensitivity reactions have occurred. To date and to the best of our knowledge, only two other cases requiring vein excision have been reported, an...

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Main Authors: Christopher D. Louden, BS, Jennifer Clark, PA-C, Federico Yanquez, MD, Nicos Labropoulos, PhD, Paul DiMaggio, MD, Luis R. Leon, Jr., MD, RVT
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of Vascular Surgery Cases and Innovative Techniques
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2468428723002186
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author Christopher D. Louden, BS
Jennifer Clark, PA-C
Federico Yanquez, MD
Nicos Labropoulos, PhD
Paul DiMaggio, MD
Luis R. Leon, Jr., MD, RVT
author_facet Christopher D. Louden, BS
Jennifer Clark, PA-C
Federico Yanquez, MD
Nicos Labropoulos, PhD
Paul DiMaggio, MD
Luis R. Leon, Jr., MD, RVT
author_sort Christopher D. Louden, BS
collection DOAJ
description Hypersensitivity reactions after endovenous ablation with cyanoacrylate are relatively common, mild, and self-limited. However, rare cases of severe hypersensitivity reactions have occurred. To date and to the best of our knowledge, only two other cases requiring vein excision have been reported, and we present the third. Even rarer are cases with severe reactions featuring cyanoacrylate extravasation with skin perforation. In the present report, we describe the second case of skin perforation after successful cyanoacrylate endovenous glue embolization. The mechanism of these severe hypersensitivity reactions is unknown. Clinicians should to consider this as a possible complication when using cyanoacrylate. Although rare, patients should also be advised of this adverse event when considering this alternative.
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spelling doaj.art-546fed0fe558449c97a3f175aff935302023-12-20T07:35:13ZengElsevierJournal of Vascular Surgery Cases and Innovative Techniques2468-42872023-12-0194101309Severe adverse reactions after cyanoacrylate endovenous ablationChristopher D. Louden, BS0Jennifer Clark, PA-C1Federico Yanquez, MD2Nicos Labropoulos, PhD3Paul DiMaggio, MD4Luis R. Leon, Jr., MD, RVT5Department of Physiology, University of Arizona, Tucson, AZVascular and Endovascular Surgery, US Heart and Vascular, Nashville, TNDepartment of Pathology, Tucson Medical Center, Tucson, AZVascular and Endovascular Surgery, Stony Brook University, Stony Brook, NYDepartment of Pathology, Tucson Medical Center, Tucson, AZDepartment of Physiology, University of Arizona, Tucson, AZ; Correspondence: Luis R. Leon, Jr., MD, RVT, Vascular and Endovascular Surgery, The University of Arizona, 801 E Calle Elena, Tucson, AZ 85721Hypersensitivity reactions after endovenous ablation with cyanoacrylate are relatively common, mild, and self-limited. However, rare cases of severe hypersensitivity reactions have occurred. To date and to the best of our knowledge, only two other cases requiring vein excision have been reported, and we present the third. Even rarer are cases with severe reactions featuring cyanoacrylate extravasation with skin perforation. In the present report, we describe the second case of skin perforation after successful cyanoacrylate endovenous glue embolization. The mechanism of these severe hypersensitivity reactions is unknown. Clinicians should to consider this as a possible complication when using cyanoacrylate. Although rare, patients should also be advised of this adverse event when considering this alternative.http://www.sciencedirect.com/science/article/pii/S2468428723002186CyanoacrylateEndovenous ablationHypersensitivityMinimally invasive
spellingShingle Christopher D. Louden, BS
Jennifer Clark, PA-C
Federico Yanquez, MD
Nicos Labropoulos, PhD
Paul DiMaggio, MD
Luis R. Leon, Jr., MD, RVT
Severe adverse reactions after cyanoacrylate endovenous ablation
Journal of Vascular Surgery Cases and Innovative Techniques
Cyanoacrylate
Endovenous ablation
Hypersensitivity
Minimally invasive
title Severe adverse reactions after cyanoacrylate endovenous ablation
title_full Severe adverse reactions after cyanoacrylate endovenous ablation
title_fullStr Severe adverse reactions after cyanoacrylate endovenous ablation
title_full_unstemmed Severe adverse reactions after cyanoacrylate endovenous ablation
title_short Severe adverse reactions after cyanoacrylate endovenous ablation
title_sort severe adverse reactions after cyanoacrylate endovenous ablation
topic Cyanoacrylate
Endovenous ablation
Hypersensitivity
Minimally invasive
url http://www.sciencedirect.com/science/article/pii/S2468428723002186
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AT nicoslabropoulosphd severeadversereactionsaftercyanoacrylateendovenousablation
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