Re-emergence of human T-lymphotropic viruses in West Africa
Human T-lymphotropic viruses (HTLV) are Deltaretroviruses that infect millions of individuals worldwide via the same transmission routes as HIV. With the aim of exposing the possible re-emergence of HTLV in West Africa since discovery, a systematic review was carried out, focusing on the distributio...
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| Format: | Article |
| Language: | English |
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Elsevier
2018-05-01
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| Series: | Brazilian Journal of Infectious Diseases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1413867018301582 |
| _version_ | 1818554186510368768 |
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| author | Nneoma Confidence JeanStephanie Anyanwu Elijah Ekah Ella Aghogho Ohwofasa Maryam Aminu |
| author_facet | Nneoma Confidence JeanStephanie Anyanwu Elijah Ekah Ella Aghogho Ohwofasa Maryam Aminu |
| author_sort | Nneoma Confidence JeanStephanie Anyanwu |
| collection | DOAJ |
| description | Human T-lymphotropic viruses (HTLV) are Deltaretroviruses that infect millions of individuals worldwide via the same transmission routes as HIV. With the aim of exposing the possible re-emergence of HTLV in West Africa since discovery, a systematic review was carried out, focusing on the distribution of the virus types and significance of frequent indeterminate reports, while highlighting the need for mandatory routine blood screening. Capturing relevant data from discovery till date, sources searched were Google Scholar, CrossRef, NCBI (PubMed), MEDLINE, Research Gate, Mendeley, abstracts of Conferences and Proceedings, organization websites and reference lists of selected papers. A total of 2626 references were initially retrieved using search terms: Worldwide prevalence of HTLV, HTLV in Africa, HTLV in West Africa, HTLV subtypes, HTLV 3 and 4 in Africa, HTLV of African origin, HTLV seroindeterminate results, Spread of HTLV. These references were rigorously trimmed down to 76. Although evidence shows that HTLV is still endemic in the region, West Africa lacks recent epidemiological prevalence data. Thorough investigations are needed to ascertain the true cause of indeterminate Western Blot results. It is imperative that routine screening for HTLVs be mandated in West African health care facilities. Keywords: HTLV in West Africa, Worldwide distribution, Epidemiology, HAM/TSP, Seroindeterminate individuals, Blood transfusion, ATLL |
| first_indexed | 2024-12-12T09:36:03Z |
| format | Article |
| id | doaj.art-54713e2b9c2d4ccda76978f753540e9f |
| institution | Directory Open Access Journal |
| issn | 1413-8670 |
| language | English |
| last_indexed | 2024-12-12T09:36:03Z |
| publishDate | 2018-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Infectious Diseases |
| spelling | doaj.art-54713e2b9c2d4ccda76978f753540e9f2022-12-22T00:28:43ZengElsevierBrazilian Journal of Infectious Diseases1413-86702018-05-01223224234Re-emergence of human T-lymphotropic viruses in West AfricaNneoma Confidence JeanStephanie Anyanwu0Elijah Ekah Ella1Aghogho Ohwofasa2Maryam Aminu3Ahmadu Bello University, Faculty of Life Sciences, Department of Microbiology, Zaria, Nigeria; COMSATS University, Department of Biosciences, Islamabad, Pakistan; Corresponding author.Ahmadu Bello University, Faculty of Life Sciences, Department of Microbiology, Zaria, NigeriaCOMSATS University, Department of Biosciences, Islamabad, PakistanAhmadu Bello University, Faculty of Life Sciences, Department of Microbiology, Zaria, NigeriaHuman T-lymphotropic viruses (HTLV) are Deltaretroviruses that infect millions of individuals worldwide via the same transmission routes as HIV. With the aim of exposing the possible re-emergence of HTLV in West Africa since discovery, a systematic review was carried out, focusing on the distribution of the virus types and significance of frequent indeterminate reports, while highlighting the need for mandatory routine blood screening. Capturing relevant data from discovery till date, sources searched were Google Scholar, CrossRef, NCBI (PubMed), MEDLINE, Research Gate, Mendeley, abstracts of Conferences and Proceedings, organization websites and reference lists of selected papers. A total of 2626 references were initially retrieved using search terms: Worldwide prevalence of HTLV, HTLV in Africa, HTLV in West Africa, HTLV subtypes, HTLV 3 and 4 in Africa, HTLV of African origin, HTLV seroindeterminate results, Spread of HTLV. These references were rigorously trimmed down to 76. Although evidence shows that HTLV is still endemic in the region, West Africa lacks recent epidemiological prevalence data. Thorough investigations are needed to ascertain the true cause of indeterminate Western Blot results. It is imperative that routine screening for HTLVs be mandated in West African health care facilities. Keywords: HTLV in West Africa, Worldwide distribution, Epidemiology, HAM/TSP, Seroindeterminate individuals, Blood transfusion, ATLLhttp://www.sciencedirect.com/science/article/pii/S1413867018301582 |
| spellingShingle | Nneoma Confidence JeanStephanie Anyanwu Elijah Ekah Ella Aghogho Ohwofasa Maryam Aminu Re-emergence of human T-lymphotropic viruses in West Africa Brazilian Journal of Infectious Diseases |
| title | Re-emergence of human T-lymphotropic viruses in West Africa |
| title_full | Re-emergence of human T-lymphotropic viruses in West Africa |
| title_fullStr | Re-emergence of human T-lymphotropic viruses in West Africa |
| title_full_unstemmed | Re-emergence of human T-lymphotropic viruses in West Africa |
| title_short | Re-emergence of human T-lymphotropic viruses in West Africa |
| title_sort | re emergence of human t lymphotropic viruses in west africa |
| url | http://www.sciencedirect.com/science/article/pii/S1413867018301582 |
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