Heme on innate immunity and inflammation

Heme on innate immunity and inflammation

Heme is an essential molecule expressed ubiquitously all through our tissues. Heme plays major functions in cellular physiology and metabolism as the prostetic group of diverse proteins. Once released from cells and from hemeproteins free heme causes oxidative damage and inflammation, thus acting as...

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Bibliographic Details
Main Authors: Fabianno Ferreira Dutra, Marcelo Torres Bozza
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Pharmacology
Subjects:
Heme
Hemolysis
Inflammation
Iron
innate immunity
Cytotoxicity
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00115/full

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