Defining the Role of Solid Stress and Matrix Stiffness in Cancer Cell Proliferation and Metastasis
Solid tumors are characterized by an abnormal stroma that contributes to the development of biomechanical abnormalities in the tumor microenvironment. In particular, these abnormalities include an increase in matrix stiffness and an accumulation of solid stress in the tumor interior. So far, it is n...
Main Authors: | Maria Kalli, Triantafyllos Stylianopoulos |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-03-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fonc.2018.00055/full |
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