Luteolin Attenuates Hypertension via Inhibiting NF-κB-Mediated Inflammation and PI3K/Akt Signaling Pathway in the Hypothalamic Paraventricular Nucleus

Luteolin Attenuates Hypertension via Inhibiting NF-κB-Mediated Inflammation and PI3K/Akt Signaling Pathway in the Hypothalamic Paraventricular Nucleus

Background: Luteolin is widely distributed among a number of vegetal species worldwide. The pharmacological effects of luteolin are diverse and amongst antioxidant, free radical scavenging, and anti-inflammatory activities. Preliminary study showed that luteolin can ameliorate hypertension. However,...

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Bibliographic Details
Main Authors: Hong-Li Gao, Xiao-Jing Yu, Yu-Qi Feng, Yu Yang, Han-Bo Hu, Yu-Yang Zhao, Jia-Hao Zhang, Kai-Li Liu, Yan Zhang, Li-Yan Fu, Ying Li, Jie Qi, Jin-An Qiao, Yu-Ming Kang
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Nutrients
Subjects:
luteolin
hypothalamic paraventricular nucleus
PI3K/Akt/NF-κB signaling pathway
infammatory cytokines
oxidative stress
hypertension
Online Access:https://www.mdpi.com/2072-6643/15/3/502

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https://www.mdpi.com/2072-6643/15/3/502

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