Chronic ethanol exposure impairs alveolar leukocyte infiltration during pneumococcal pneumonia, leading to an increased bacterial burden despite increased CXCL1 and nitric oxide levels

Chronic ethanol exposure impairs alveolar leukocyte infiltration during pneumococcal pneumonia, leading to an increased bacterial burden despite increased CXCL1 and nitric oxide levels

Ethanol abuse is a risk factor for the development of pneumonia caused by Streptococcus pneumoniae, a critical pathogen for public health. The aim of this article was to investigate the inflammatory mechanisms involved in pneumococcal pneumonia that may be associated with chronic ethanol exposure. M...

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Bibliographic Details
Main Authors: Flávia Rayssa Braga Martins, Maycon Douglas de Oliveira, Jéssica Amanda Marques Souza, Celso Martins Queiroz-Junior, Francisco Pereira Lobo, Mauro Martins Teixeira, Nathalia Luisa Malacco, Frederico Marianetti Soriani
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
alcohol
nitric oxide
pneumonia
streptococcus pneumoniae
CXCL1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1175275/full

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