Functional evolution of cis-regulatory modules at a homeotic gene in Drosophila.

Functional evolution of cis-regulatory modules at a homeotic gene in Drosophila.

It is a long-held belief in evolutionary biology that the rate of molecular evolution for a given DNA sequence is inversely related to the level of functional constraint. This belief holds true for the protein-coding homeotic (Hox) genes originally discovered in Drosophila melanogaster. Expression o...

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Bibliographic Details
Main Authors:	Margaret C W Ho, Holly Johnsen, Sara E Goetz, Benjamin J Schiller, Esther Bae, Diana A Tran, Andrey S Shur, John M Allen, Christoph Rau, Welcome Bender, William W Fisher, Susan E Celniker, Robert A Drewell
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2009-11-01
Series:	PLoS Genetics
Online Access:	http://europepmc.org/articles/PMC2763271?pdf=render

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