Impact of Exercise Training at Different Intensity Levels on Cardiac Function and Exercise Capacity in Patients with Chronic Heart Failure: A Prospective Cohort Study
Objective: To investigate training at different intensity levels on cardiac function, exercise capacity, and health-related quality of life in patients with chronic heart failure. Methods: This prospective cohort study enrolled patients with chronic heart failure at Beijing Rehabilitation Hospital,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Medical Journals Sweden
2022-11-01
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| Series: | Journal of Rehabilitation Medicine |
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| Online Access: | https://medicaljournalssweden.se/jrm/article/view/1023 |
| _version_ | 1811334374467043328 |
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| author | Zhenying Zhang Lizhong Wang Jianing Xi Xiaojing Sun Xingguo Sun |
| author_facet | Zhenying Zhang Lizhong Wang Jianing Xi Xiaojing Sun Xingguo Sun |
| author_sort | Zhenying Zhang |
| collection | DOAJ |
| description |
Objective: To investigate training at different intensity levels on cardiac function, exercise capacity, and health-related quality of life in patients with chronic heart failure.
Methods: This prospective cohort study enrolled patients with chronic heart failure at Beijing Rehabilitation Hospital, Beijing, China from January 2018 to January 2020. Participants received conventional therapy (non-exercise group) or therapy plus cycle ergometer exercises at an intensity of 80% anaerobic threshold (EA group) and Δ50% power above anaerobic threshold (EB group) for 12 weeks. The primary outcome was peak oxygen uptake.
Results: Forty-five patients (15/group) completed the study without serious complications. Exercise training at an intensity of Δ50% power above anaerobic threshold had better effects on exercise capacity than exercise at an intensity of 80% anaerobic threshold, as shown by a greater improvement in peak oxygen uptake (20.3 ± 4.1 vs 16.8 ± 3.2 mL/min/kg), peak O2 pulse (12.5 ± 2.3 vs 10.1 ± 2.1 mL/beat), and peak workload (123.1 ± 26.9 vs 102.8 ± 29.5 W) in patients with chronic heart failure (all p < 0.001). Exercise improved the 6-min walk test distance (control: 394.0 ± 74.1; EA: 481.4 ± 89.4; EB: 508.9 ± 92.5 m; p < 0.001) and health-related quality of life (control: 40.7 ± 12.3; EA: 16.2 ± 8.6; EB: 11.5 ± 6.4; p < 0.001).
Conclusion: Compared with an intensity of 80% anaerobic threshold, exercise training at an intensity of Δ 50% power above anaerobic threshold was safe and had better effects on cardiac function, exercise capacity, and health-related quality of life.
LAY ABSTRACT
The aim of this study was to investigate training at different intensity levels on cardiac function, exercise capacity, and health-related quality of life in patients with chronic heart failure. Exercise training at an intensity of Δ 50% power above anaerobic threshold (mild anaerobic exercise) had better effects on exercise capacity than non-exercise and intensity of 80% anaerobic threshold (aerobic exercise). In addition, exercise resulted in improved health-related quality of life compared with non-exercise. Therefore, the benefit may be greater if the exercise intensity is increased appropriately under safe conditions.
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| first_indexed | 2024-04-13T17:06:59Z |
| format | Article |
| id | doaj.art-54831cc50a1d40719b386e0e1b2d9876 |
| institution | Directory Open Access Journal |
| issn | 1651-2081 |
| language | English |
| last_indexed | 2024-04-13T17:06:59Z |
| publishDate | 2022-11-01 |
| publisher | Medical Journals Sweden |
| record_format | Article |
| series | Journal of Rehabilitation Medicine |
| spelling | doaj.art-54831cc50a1d40719b386e0e1b2d98762022-12-22T02:38:25ZengMedical Journals SwedenJournal of Rehabilitation Medicine1651-20812022-11-015410.2340/jrm.v54.1023Impact of Exercise Training at Different Intensity Levels on Cardiac Function and Exercise Capacity in Patients with Chronic Heart Failure: A Prospective Cohort StudyZhenying Zhang0Lizhong Wang1Jianing Xi2Xiaojing Sun3Xingguo Sun4Cardiac Rehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical UniversityCardiac Rehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical UniversityCardiac Rehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical UniversityNational Center for Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing, ChinaNational Center for Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing, China Objective: To investigate training at different intensity levels on cardiac function, exercise capacity, and health-related quality of life in patients with chronic heart failure. Methods: This prospective cohort study enrolled patients with chronic heart failure at Beijing Rehabilitation Hospital, Beijing, China from January 2018 to January 2020. Participants received conventional therapy (non-exercise group) or therapy plus cycle ergometer exercises at an intensity of 80% anaerobic threshold (EA group) and Δ50% power above anaerobic threshold (EB group) for 12 weeks. The primary outcome was peak oxygen uptake. Results: Forty-five patients (15/group) completed the study without serious complications. Exercise training at an intensity of Δ50% power above anaerobic threshold had better effects on exercise capacity than exercise at an intensity of 80% anaerobic threshold, as shown by a greater improvement in peak oxygen uptake (20.3 ± 4.1 vs 16.8 ± 3.2 mL/min/kg), peak O2 pulse (12.5 ± 2.3 vs 10.1 ± 2.1 mL/beat), and peak workload (123.1 ± 26.9 vs 102.8 ± 29.5 W) in patients with chronic heart failure (all p < 0.001). Exercise improved the 6-min walk test distance (control: 394.0 ± 74.1; EA: 481.4 ± 89.4; EB: 508.9 ± 92.5 m; p < 0.001) and health-related quality of life (control: 40.7 ± 12.3; EA: 16.2 ± 8.6; EB: 11.5 ± 6.4; p < 0.001). Conclusion: Compared with an intensity of 80% anaerobic threshold, exercise training at an intensity of Δ 50% power above anaerobic threshold was safe and had better effects on cardiac function, exercise capacity, and health-related quality of life. LAY ABSTRACT The aim of this study was to investigate training at different intensity levels on cardiac function, exercise capacity, and health-related quality of life in patients with chronic heart failure. Exercise training at an intensity of Δ 50% power above anaerobic threshold (mild anaerobic exercise) had better effects on exercise capacity than non-exercise and intensity of 80% anaerobic threshold (aerobic exercise). In addition, exercise resulted in improved health-related quality of life compared with non-exercise. Therefore, the benefit may be greater if the exercise intensity is increased appropriately under safe conditions. https://medicaljournalssweden.se/jrm/article/view/1023heart failurecardiac rehabilitationexercise testexercise tolerancepeak oxygen uptakeleft ventricular function |
| spellingShingle | Zhenying Zhang Lizhong Wang Jianing Xi Xiaojing Sun Xingguo Sun Impact of Exercise Training at Different Intensity Levels on Cardiac Function and Exercise Capacity in Patients with Chronic Heart Failure: A Prospective Cohort Study Journal of Rehabilitation Medicine heart failure cardiac rehabilitation exercise test exercise tolerance peak oxygen uptake left ventricular function |
| title | Impact of Exercise Training at Different Intensity Levels on Cardiac Function and Exercise Capacity in Patients with Chronic Heart Failure: A Prospective Cohort Study |
| title_full | Impact of Exercise Training at Different Intensity Levels on Cardiac Function and Exercise Capacity in Patients with Chronic Heart Failure: A Prospective Cohort Study |
| title_fullStr | Impact of Exercise Training at Different Intensity Levels on Cardiac Function and Exercise Capacity in Patients with Chronic Heart Failure: A Prospective Cohort Study |
| title_full_unstemmed | Impact of Exercise Training at Different Intensity Levels on Cardiac Function and Exercise Capacity in Patients with Chronic Heart Failure: A Prospective Cohort Study |
| title_short | Impact of Exercise Training at Different Intensity Levels on Cardiac Function and Exercise Capacity in Patients with Chronic Heart Failure: A Prospective Cohort Study |
| title_sort | impact of exercise training at different intensity levels on cardiac function and exercise capacity in patients with chronic heart failure a prospective cohort study |
| topic | heart failure cardiac rehabilitation exercise test exercise tolerance peak oxygen uptake left ventricular function |
| url | https://medicaljournalssweden.se/jrm/article/view/1023 |
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