Effects of a Multidisciplinary Residential Nutritional Rehabilitation Program in Head and Neck Cancer Survivors—Results from the NUTRI-HAB Randomized Controlled Trial
Head and neck cancer survivors frequently experience nutritional challenges, and proper rehabilitation should be offered. The trial objective was to test the effect of a multidisciplinary residential nutritional rehabilitation programme addressing physical, psychological, and social aspects of eatin...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-07-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/12/7/2117 |
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| author | Marianne Boll Kristensen Irene Wessel Anne Marie Beck Karin B. Dieperink Tina Broby Mikkelsen Jens-Jakob Kjer Møller Ann-Dorthe Zwisler |
| author_facet | Marianne Boll Kristensen Irene Wessel Anne Marie Beck Karin B. Dieperink Tina Broby Mikkelsen Jens-Jakob Kjer Møller Ann-Dorthe Zwisler |
| author_sort | Marianne Boll Kristensen |
| collection | DOAJ |
| description | Head and neck cancer survivors frequently experience nutritional challenges, and proper rehabilitation should be offered. The trial objective was to test the effect of a multidisciplinary residential nutritional rehabilitation programme addressing physical, psychological, and social aspects of eating problems after treatment. In a randomized controlled trial, 71 head and neck cancer survivors recruited through a nationwide survey were randomized to the program or a wait-list control group. Inclusion was based on self-reported interest in participation. The primary outcome was change in body weight. Secondary outcomes included physical function, quality of life, and symptoms of anxiety and depression. Differences between groups at the 3-month follow-up were tested. No significant differences were seen in body weight change, but there were overall trends towards greater improvements in physical function (hand grip strength: <i>p</i> = 0.042; maximal mouth opening: <i>p</i> = 0.072) and quality of life (“Role functioning”: <i>p</i> = 0.041; “Speech problems”: <i>p</i> = 0.040; “Pain”: <i>p</i> = 0.048) in the intervention group. To conclude, a multidisciplinary residential nutritional rehabilitation program had no effect on body weight in head and neck cancer survivors with self-reported interest in participation, but it may have effect on physical function and quality of life. Further research on relevant outcomes, inclusion criteria, and the program’s effect in different subgroups is needed. |
| first_indexed | 2024-03-10T18:25:43Z |
| format | Article |
| id | doaj.art-5485e36b778540fdb60b32fb3c062244 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T18:25:43Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-5485e36b778540fdb60b32fb3c0622442023-11-20T07:02:31ZengMDPI AGNutrients2072-66432020-07-01127211710.3390/nu12072117Effects of a Multidisciplinary Residential Nutritional Rehabilitation Program in Head and Neck Cancer Survivors—Results from the NUTRI-HAB Randomized Controlled TrialMarianne Boll Kristensen0Irene Wessel1Anne Marie Beck2Karin B. Dieperink3Tina Broby Mikkelsen4Jens-Jakob Kjer Møller5Ann-Dorthe Zwisler6Department of Nursing and Nutrition, University College Copenhagen, Sigurdsgade 26, 2200 Copenhagen N, DenmarkDepartment of Otorhinolaryngology, Head and Neck Surgery & Audiology, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ø, DenmarkDepartment of Nursing and Nutrition, University College Copenhagen, Sigurdsgade 26, 2200 Copenhagen N, DenmarkResearch Unit of Oncology, Department of Oncology, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense C, DenmarkREHPA, The Danish Knowledge Centre for Rehabilitation and Palliative Care, Odense University Hospital, and Department of Clinical Research, University of Southern Denmark, Vestergade 17, 5800 Nyborg, DenmarkREHPA, The Danish Knowledge Centre for Rehabilitation and Palliative Care, Odense University Hospital, and Department of Clinical Research, University of Southern Denmark, Vestergade 17, 5800 Nyborg, DenmarkREHPA, The Danish Knowledge Centre for Rehabilitation and Palliative Care, Odense University Hospital, and Department of Clinical Research, University of Southern Denmark, Vestergade 17, 5800 Nyborg, DenmarkHead and neck cancer survivors frequently experience nutritional challenges, and proper rehabilitation should be offered. The trial objective was to test the effect of a multidisciplinary residential nutritional rehabilitation programme addressing physical, psychological, and social aspects of eating problems after treatment. In a randomized controlled trial, 71 head and neck cancer survivors recruited through a nationwide survey were randomized to the program or a wait-list control group. Inclusion was based on self-reported interest in participation. The primary outcome was change in body weight. Secondary outcomes included physical function, quality of life, and symptoms of anxiety and depression. Differences between groups at the 3-month follow-up were tested. No significant differences were seen in body weight change, but there were overall trends towards greater improvements in physical function (hand grip strength: <i>p</i> = 0.042; maximal mouth opening: <i>p</i> = 0.072) and quality of life (“Role functioning”: <i>p</i> = 0.041; “Speech problems”: <i>p</i> = 0.040; “Pain”: <i>p</i> = 0.048) in the intervention group. To conclude, a multidisciplinary residential nutritional rehabilitation program had no effect on body weight in head and neck cancer survivors with self-reported interest in participation, but it may have effect on physical function and quality of life. Further research on relevant outcomes, inclusion criteria, and the program’s effect in different subgroups is needed.https://www.mdpi.com/2072-6643/12/7/2117head and neck cancerrehabilitationsurvivorshipeating problemslate effectsquality of life |
| spellingShingle | Marianne Boll Kristensen Irene Wessel Anne Marie Beck Karin B. Dieperink Tina Broby Mikkelsen Jens-Jakob Kjer Møller Ann-Dorthe Zwisler Effects of a Multidisciplinary Residential Nutritional Rehabilitation Program in Head and Neck Cancer Survivors—Results from the NUTRI-HAB Randomized Controlled Trial Nutrients head and neck cancer rehabilitation survivorship eating problems late effects quality of life |
| title | Effects of a Multidisciplinary Residential Nutritional Rehabilitation Program in Head and Neck Cancer Survivors—Results from the NUTRI-HAB Randomized Controlled Trial |
| title_full | Effects of a Multidisciplinary Residential Nutritional Rehabilitation Program in Head and Neck Cancer Survivors—Results from the NUTRI-HAB Randomized Controlled Trial |
| title_fullStr | Effects of a Multidisciplinary Residential Nutritional Rehabilitation Program in Head and Neck Cancer Survivors—Results from the NUTRI-HAB Randomized Controlled Trial |
| title_full_unstemmed | Effects of a Multidisciplinary Residential Nutritional Rehabilitation Program in Head and Neck Cancer Survivors—Results from the NUTRI-HAB Randomized Controlled Trial |
| title_short | Effects of a Multidisciplinary Residential Nutritional Rehabilitation Program in Head and Neck Cancer Survivors—Results from the NUTRI-HAB Randomized Controlled Trial |
| title_sort | effects of a multidisciplinary residential nutritional rehabilitation program in head and neck cancer survivors results from the nutri hab randomized controlled trial |
| topic | head and neck cancer rehabilitation survivorship eating problems late effects quality of life |
| url | https://www.mdpi.com/2072-6643/12/7/2117 |
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