“I know why I am taking this pill”: Young women navigation of disclosure and support for PrEP uptake and adherence in Eastern Cape Province, South Africa
There is limited understanding of the dynamic interplay between adolescent girl’s and young women’s (AGYW) disclosure and social support for using oral pre-exposure prophylaxis (PrEP) and adherence. Towards this, we conducted interviews with 42 AGYW enrolled in The Community PrEP Study who exhibited...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2023-01-01
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| Series: | PLOS Global Public Health |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021316/?tool=EBI |
| _version_ | 1797702558663311360 |
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| author | Joseph Daniels Lindsey De Vos Dana Bezuidenhout Millicent Atujuna Connie Celum Sybil Hosek Linda-Gail Bekker Andrew Medina-Marino |
| author_facet | Joseph Daniels Lindsey De Vos Dana Bezuidenhout Millicent Atujuna Connie Celum Sybil Hosek Linda-Gail Bekker Andrew Medina-Marino |
| author_sort | Joseph Daniels |
| collection | DOAJ |
| description | There is limited understanding of the dynamic interplay between adolescent girl’s and young women’s (AGYW) disclosure and social support for using oral pre-exposure prophylaxis (PrEP) and adherence. Towards this, we conducted interviews with 42 AGYW enrolled in The Community PrEP Study who exhibited either high or low blood concentrations of tenofovir-diphosphate (TFV-DP) in dried blood spots. Guided by Theories of Practice, interviews and analysis focused on AGYW perspectives and experiences with PrEP disclosure, support and adherence. AGYW with high TFV-DP blood concentrations described larger social support networks and disclosure events. In contrast, those with low TFV-DP blood concentrations described disclosing to fewer people, resulting in limited social support. Participants discussed partner support, however, this support was not described as consequential to adherence, irrespective of TFV-DP levels. Those with high levels of TFV-DP in their blood described the ability to navigate social scrutiny and changes in social support, while those with low levels of TFV-DP in their blood were more likely to question their own continued use of PrEP. To facilitate AGYW’s prevention-effective use of PrEP, expanded skill-building for disclosure and resiliency against changes to social support should be examined as part of PrEP services. |
| first_indexed | 2024-03-12T04:51:45Z |
| format | Article |
| id | doaj.art-5488a50de8da497abf7750c53ea2fe79 |
| institution | Directory Open Access Journal |
| issn | 2767-3375 |
| language | English |
| last_indexed | 2024-03-12T04:51:45Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLOS Global Public Health |
| spelling | doaj.art-5488a50de8da497abf7750c53ea2fe792023-09-03T09:20:30ZengPublic Library of Science (PLoS)PLOS Global Public Health2767-33752023-01-0131“I know why I am taking this pill”: Young women navigation of disclosure and support for PrEP uptake and adherence in Eastern Cape Province, South AfricaJoseph DanielsLindsey De VosDana BezuidenhoutMillicent AtujunaConnie CelumSybil HosekLinda-Gail BekkerAndrew Medina-MarinoThere is limited understanding of the dynamic interplay between adolescent girl’s and young women’s (AGYW) disclosure and social support for using oral pre-exposure prophylaxis (PrEP) and adherence. Towards this, we conducted interviews with 42 AGYW enrolled in The Community PrEP Study who exhibited either high or low blood concentrations of tenofovir-diphosphate (TFV-DP) in dried blood spots. Guided by Theories of Practice, interviews and analysis focused on AGYW perspectives and experiences with PrEP disclosure, support and adherence. AGYW with high TFV-DP blood concentrations described larger social support networks and disclosure events. In contrast, those with low TFV-DP blood concentrations described disclosing to fewer people, resulting in limited social support. Participants discussed partner support, however, this support was not described as consequential to adherence, irrespective of TFV-DP levels. Those with high levels of TFV-DP in their blood described the ability to navigate social scrutiny and changes in social support, while those with low levels of TFV-DP in their blood were more likely to question their own continued use of PrEP. To facilitate AGYW’s prevention-effective use of PrEP, expanded skill-building for disclosure and resiliency against changes to social support should be examined as part of PrEP services.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021316/?tool=EBI |
| spellingShingle | Joseph Daniels Lindsey De Vos Dana Bezuidenhout Millicent Atujuna Connie Celum Sybil Hosek Linda-Gail Bekker Andrew Medina-Marino “I know why I am taking this pill”: Young women navigation of disclosure and support for PrEP uptake and adherence in Eastern Cape Province, South Africa PLOS Global Public Health |
| title | “I know why I am taking this pill”: Young women navigation of disclosure and support for PrEP uptake and adherence in Eastern Cape Province, South Africa |
| title_full | “I know why I am taking this pill”: Young women navigation of disclosure and support for PrEP uptake and adherence in Eastern Cape Province, South Africa |
| title_fullStr | “I know why I am taking this pill”: Young women navigation of disclosure and support for PrEP uptake and adherence in Eastern Cape Province, South Africa |
| title_full_unstemmed | “I know why I am taking this pill”: Young women navigation of disclosure and support for PrEP uptake and adherence in Eastern Cape Province, South Africa |
| title_short | “I know why I am taking this pill”: Young women navigation of disclosure and support for PrEP uptake and adherence in Eastern Cape Province, South Africa |
| title_sort | i know why i am taking this pill young women navigation of disclosure and support for prep uptake and adherence in eastern cape province south africa |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021316/?tool=EBI |
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