Predictive models in SMA II natural history trajectories using machine learning: A proof of concept study.
It is known from previous literature that type II Spinal Muscular Atrophy (SMA) patients generally, after the age of 5 years, presents a steep deterioration until puberty followed by a relative stability, as most abilities have been lost. Although it is possible to identify points of slope indicatin...
Main Authors: | Giorgia Coratti, Jacopo Lenkowicz, Stefano Patarnello, Consolato Gullì, Maria Carmela Pera, Carlotta Masciocchi, Riccardo Rinaldi, Valeria Lovato, Antonio Leone, Alfredo Cesario, Eugenio Mercuri |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0267930 |
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